|10247013||Faculty of Health Sciences|
|Minimum duration of study: 1 year||Total credits: 120|
Students who did not register at undergraduate level (i.e. from the second year of study) in Nuclear Medicine, register according to this curriculum.
All students must register for NVB 700 Research principles.
Also consult the General Regulations.
Minimum credits: 120
Development and submission of a research protocol.
Module consists of two sections to integrate with theoretical knowledge gained in TKG 710 (Theory of nuclear medicine). Clinical practice to operationalise and integrate the fundamental theoretical components. Choice of examination, patient positioning, field of view, orientation, routine views, static and dynamic imaging, SPECT imaging, modified views, acquisition and processing of data, correct labelling of data, patient care. Quality control. Pattern recognition and interpretation of procedures. Problems and pitfalls. Hot laboratory rules, regulations, skills, calculations. Cold laboratory equipment and procedures. Application of radiation safety. Advanced imaging and processing techniques. Procedures involving the use of emerging technologies and radiopharmaceuticals. Paediatric nuclear medicine diagnostic imaging. Management and administration of therapeutic radiopharmaceuticals. Radiation safety aspects. Comprehensive quality assurance and unit management. Establishing nuclear medicine services. Advanced concepts, current quality management theory, accreditation, and audit documentation. Basic principles and practices necessary for effective supervision and leadership in a healthcare environment. Principles and practices in human resource management in healthcare settings.
Definitions, principles, concepts, terminology, notation. Production and purification of radionuclides. Generators: working knowledge, evaluation techniques, quality control. Technegas production. Radiolabelling methods. Characteristics and quality control of radiopharmaceuticals. Biodistribution, pharmacokinetics, metabolism of radiopharmaceuticals. Kit preparation. Diagnostic and therapeutic radiopharmaceuticals, requirements, radiobiological aspects and applications. Hot laboratory: Rules and regulations. Type A, B, C laboratories. Radiopharmacy construction and design. Radiation safety and protection. Relevant instrumentation and equipment hot and cold lab. Handling, storage and waste disposal of radioactive materials. Contamination and decontamination procedures. Radiopharmaceuticals: preparation, dose calculation and measurement. Molecular imaging. Adverse reactions and altered biodistribution.
Continuation of the research process which includes the implementation of the approved research protocol and writing up a research essay of the completed research project.
Basic concepts of radiation physics, radioactive decay, radionuclide production, interaction with matter, radiation detectors and counting systems. Problems in radiation detection. The gamma camera: performance, image quality, quality control. Digital computers in nuclear medicine. SPECT principles, cameras, quality. PET principles, cameras, quality. Radiation dosimetry and biology. Radiation protection and safety.
Revision of relevant anatomy, physiology and pathology. Procedures of musculoskeletal, endocrine, respiratory, genito-urinary, gastro-intestinal, hepatobiliary, cardiovascular, central nervous systems. Infection and SPECT imaging. Procedures including lymphatics, venograms, ciliary clearance, dacyroscintigraphy. Non-imaging procedures. Radio-immunoassays: History, basic principles, antibody production. Monoclonal antibodies. Radioimmunoscintigraphy. Radiation safety. Tumour imaging and therapeutic procedures. Paediatric techniques. PET and PET/CT. Indications and contra-indications. Effects of medication on procedures. Drug intervention. Radiopharmaceuticals: methods of administration, choice, physiological pathways, patient dose, quality control. Instrumentation, collimation, settings, quality control. Patient treatment: patient preparation, instructions, route and technique of radiopharmaceutical administration. Procedures: choice of examination, patient positioning, field of view, orientation, routine views, static and dynamic imaging, SPECT imaging, modified views. Radiation effects: physical, biological and effective T½, target organs, excretory pathways, protection. Quality control. Pattern recognition and interpretation of procedures. Problems and pitfalls. Emerging and hybrid technology and applications.
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