|02240702||Faculty of Natural and Agricultural Sciences||Department: Genetics|
|Minimum duration of study: 1 year||Total credits: 135||NQF level: 08|
Note: Additional modules may be required in order to reach the desired level of competency
Minimum credits: 135
Core credits: 120
Elective credit: 15
Students with degrees in biological sciences should choose BME 780 as an elective. Students from computer science and other related backgrounds should choose BIF 704. Other additional modules may be prescribed for non-degree purposes to address shortcomings in a candidate’s undergraduate training.
General concepts in bioinformatics; sequence motifs and features; sequence databases; common bioinformatics tools; programming in Python; the bioinformatics toolkit for Python; pairwise and multiple sequence alignments; genome analysis; data visualisation; specialised statistics for bioinformatics; specialised algorithms for bioinformatics; nucleic acid modelling; transcription analysis; microarray data analysis; genome annotation; phylogenetics; mapping and markers; structural modelling.
Study and discussion of topical research results from recent scientific publications.
Principles and applications of recombinant DNA, and other novel molecular and genomics technologies, to address questions in the biological sciences and/or biotechnology. Strong emphasis is placed on the principles of research planning, including identifying suitable research objectives, formulating a research strategy and understanding the relevance and feasibility of research. The module is assessed by means of a research project proposal, conceived and formulated by each student. The proposal must focus on the use of molecular technologies in addressing realistic questions in biology and/or biotechnology. There is also an oral defense of the project proposal.
This module is jointly presented in the Departments of Biochemistry, Genetics and Microbiology and Plant and Soil Sciences.
Atoms and molecules; the chemistry of life, organisation of the cell; energy; chromosomes; heredity; DNA; RNA and protein synthesis; gene regulation; genetic engineering; genomes; genes and development; evolution; speciation; diversity.
The principles of experimental design as required for the selection of an appropriate research design. Identification of the design limitations and the impact thereof on the research hypotheses and the statistical methods. Identification and application of the appropriate statistical methods needed. Interpreting of statistical results and translating these results to the biological context.
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