Revision of relevant anatomy, physiology and pathology. Procedures of musculoskeletal, endocrine, respiratory, genito-urinary, gastro-intestinal, hepatobiliary, cardiovascular, central nervous systems. Infection and SPECT imaging. Procedures including lymphatics, venograms, ciliary clearance, dacyroscintigraphy. Non-imaging procedures. Radio-immunoassays: History, basic principles, antibody production. Monoclonal antibodies. Radioimmunoscintigraphy. Radiation safety. Tumour imaging and therapeutic procedures. Paediatric techniques. PET and PET/CT. Indications and contra-indications. Effects of medication on procedures. Drug intervention. Radiopharmaceuticals: methods of administration, choice, physiological pathways, patient dose, quality control. Instrumentation, collimation, settings, quality control. Patient treatment: patient preparation, instructions, route and technique of radiopharmaceutical administration. Procedures: choice of examination, patient positioning, field of view, orientation, routine views, static and dynamic imaging, SPECT imaging, modified views. Radiation effects: physical, biological and effective T½, target organs, excretory pathways, protection. Quality control. Pattern recognition and interpretation of procedures. Problems and pitfalls. Emerging and hybrid technology and applications.