Featured Research: Genomics & Biotechnology

  • Infographic

    Biomedical researchers are tapping into mole rats' unique adaptations

    Mole rat biology could inform human health interventions like cancer therapies, heart attack prevention, maternal health and birth control, mental health approaches, anti-ageing drugs, neurodegenerative disease treatment, and pain management.

  • Story

    UP experts contribute to discovery of new ‘superpowers’ in mole rats, which could inform human health interventions

    University of Pretoria (UP) scientists have contributed to discovering how the naked mole rat is able to withstand heart attacks and fend off bowel cancer, two of the most fatal human ailments in the developed world. Their findings were published recently in two Nature Communications papers.

  • Story

    UP researchers find environmental toxins poison epigenetic inheritance

    In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers at the University of Pretoria and Canada’s McGill University and Université Laval have concluded that toxins in the environment, notably DDT, modify the sperm epigenome at sites potentially transmitted to the embryo at conception.

  • Story

    UP researchers close in on the secret to aging

    The quest for immortality has long fascinated humans, and inspired countless tales – now, in two new studies published in the journals Nature and Science, University of Pretoria (UP) researchers, along with a team of global experts known as the Mammalian Methylation Consortium, are a step closer to unmasking the secret of aging in mammals, thus raising important questions – and answers.

  • Infographic

    Developing the pan-mammalian clock

    This infographic explains how the universal pan-mammalian clock was developed to determine the age of mammals in the wild for conservation and the preservation of endangered species. The clock can be used in forensic science to estimate the correct age of a victim at the time of death or the age of a suspect based on forensic evidence.

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    The pan-mammalian clock

    Aging has long been thought to be the result of random cellular damage or degradation over time, but this latest research shows that the epigenetic aspects of aging in fact follow a predetermined “programme”.

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