Microbes (bacteria, archaea, fungi, and viruses) are the most diverse and numerically abundant entities on our planet. However, we know surprisingly little regarding the vast microbial universe within and beyond us. The past two decades of sequencing-enabled research have revealed remarkable insights regarding the diversity and functional attributes of microbial communities, yet we lack comparative insights regarding African microbiomes. This talk will explore the importance of microbiomes in maintaining human health, as well as the challenges of studying these invisible organisms. I will highlight the unique potential of Africa’s rich biodiversity for “unlocking the secrets of microbiomes” and understanding their roles in shaping our world. I will also discuss the urgent need for increased investment in microbiome research and technology development in Africa, to ensure that the continent remains at the forefront of scientific discovery in this rapidly evolving field.
Prof Thulani Makhalanyane
May 4, 2023
Professor Thulani Makhalanyane graduated from the University of the Western Cape with an MSc (cum laude) (2009) and a PhD (2013).
After completing his doctoral studies, he moved to the University of Pretoria (UP) where his research has focused almost entirely on understanding the ecology of microbial communities in extreme environments. These habitats include soil microbial communities in the Antarctic Dry Valleys, the Namib Desert and increasingly in South African regions such as the Southern Ocean.
In 2014, after a period as a postdoctoral fellow, Prof Makhalanyane was appointed as a lecturer before being promoted to associate professor in 2019. He holds the DSI/NRF SARChI Chair in Marine Microbiomics and continues to undertake research at UP. He supervises 14 postgraduate students at master’s and doctorate levels.
Prof Makhalanyane has generated over 60 publications since 2012 (H index 25), and his work has been presented at several international meetings, including the International Symposium on Microbial Ecology. He serves on national and international panels, representing South Africa in bilateral discussions. He also serves on several editorial boards and is senior editor at three journals: the ISME Journal, mSystems and Communications Biology.
Prof Makhalanyane was elected to the board of the ISME Society in October 2018 and is a member of the Executive Advisory Board. He is a Fulbright Scholar and has received several awards, including the TW-Kambule-NSTF Award (Emerging Researcher), and was given a prestigious NRF P rating.
University of Pretoria (UP) researchers have found that the antioxidant content of certain types of tea can be likened to that found in recommended portions of fruit and vegetables.
Half a cup of black tea, oolong tea or green tea contained the same amount of antioxidants with radical scavenging capabilities (RSC) as that of a 200mg vitamin C tablet.
Researchers at the University of Pretoria (UP) may have identified the gene that is responsible for diet-related obesity. By exploring the role of the novel gene Slc7a8, they have made a potential breakthrough in current knowledge about the cellular mechanisms that drive fat accumulation. This understanding is crucial in developing effective treatments.
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