The Department of Mathematics and Applied Mathematics at the University of Pretoria is not only one of the largest departments on the Hatfield Campus but also one of the largest Mathematics departments in the country. It grew from humble beginnings in 1913, with only 38 students, to a department with more than 20 000 students enrolled on mathematics modules. The diverse and competent body of staff, including over 30 NRF-rated researchers, boasts expertise in a variety of fields. The department prides itself in excelling in both its teaching and research activities, as well as in community-based activities.

Physically, the department is situated on the western side of the campus of the University of Pretoria. The building has a classical old-time character that surrounds a quad where the bustle of students adds vibrancy. A newer feature is that of an enclosed garden that provides a popular venue for outdoor functions. The singular environment is complemented by a tangible academic atmosphere in which many UP graduates have reached success.

The department is one of the three leaders in Mathematics within the African continent according to the QS World University Rankings in 2021, 2022, 2023 and 2024.