In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers at the University of Pretoria and Canada’s McGill University and Université Laval have concluded that toxins in the environment, notably DDT, modify the sperm epigenome at sites potentially transmitted to the embryo at conception.
The quest for immortality has long fascinated humans, and inspired countless tales – now, in two new studies published in the journals Nature and Science, University of Pretoria (UP) researchers, along with a team of global experts known as the Mammalian Methylation Consortium, are a step closer to unmasking the secret of aging in mammals, thus raising important questions – and answers.
Aging has long been thought to be the result of random cellular damage or degradation over time, but this latest research shows that the epigenetic aspects of aging in fact follow a predetermined “programme”.
This infographic explains how the universal pan-mammalian clock was developed to determine the age of mammals in the wild for conservation and the preservation of endangered species. The clock can be used in forensic science to estimate the correct age of a victim at the time of death or the age of a suspect based on forensic evidence.
Researchers at the University of Pretoria (UP) have been working to identify genes that make African women more susceptible to certain forms of breast cancer. However, this is no easy task as very little genomic information is known about African populations.
This issue features research from all of the University of Pretoria's nine faculties and our business school, the Gordan Institute of Business Science (GIBS) and shows how our research is opening a new world and a better future.
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