| Student | Degree | Type | Title | Supervisors |
| Mr A Sitoe | PhD, Chemical Engineering | Thesis | Controlled-release of mosquito repellents from microporous polymer strands | Prof WW Focke |
|
Ms Masego Dilebo |
MSc, Biochemistry | Dissertation | Mechanistic investigation of novel artemisinin-based combination that targets Plasmodium falciparum parasites | Prof L Birkholtz, Dr D Coertzen, RK Haynes |
|
Ms Ashley van Heerden |
MSc, Biochemistry | Dissertation | Stratifying antimalarial compounds with similar mode of action using machine learning on chemo-transcriptome profiles | Prof L Birkholtz |
|
Ms Suzan Maboane |
MSc, Biochemistry | Dissertation | The contribution of Plasmodium falciparum genetic diversity to differentiate drug response in gametocytes | Dr J Niemand, Prof L Birkholtz |
|
Ms Dore Joubert |
MSc, Biotechnology | Dissertation | Development of a constitutive luciferase reporter line for comparable evaluation of antiplasmodial drugs on all life cycle stages of Plasmodium falciparum | Prof L Birkholtz |
|
Ms Meta Leshabane |
MSc, Biochemistry | Dissertation | Novel acid-labile and targeted nanoparticles as possible antimalarial drug-delivery systems | Prof L Birkholtz |
|
Ms Engela Theron |
MSc, Environmental Health | Dissertation | Associations between DDT and DDE uptake and male reproductive hormones with specific reference to Insulin Like Hormone-3 | Prof MS Bornman, Prof J Wichmann |
|
Ms Aamira Vally |
BSc Honours, Biochemistry | Research report | The functional importance of adenyly Cyclades alpha in Plasmodium falciparum gametocytes | Prof L Birkholtz |
|
Ms Eunice Claassen |
BSc Honours, Biochemistry | Research report | Generation of atp11-GFP-glms constructs for functional investigation of the putative aminophospholipid transporter in Plasmodium falciparum parasites | Dr J Niemand |
|
Mr Jaco van Staden |
BSc Honours, Biochemistry | Research report | Determining mitochondrial functionality in asexual intraerythricytic Plasmodium falciparum parasites | Dr D Coertzen, Prof L Birkholtz |
| Student | Degree | Type | Title | Supervisors |
| Mr S Awandu | PhD, Biochemistry | Thesis | Understanding the contribution of malaria parsites to continued residual malaria in a pre-elimnation setting in South Africa: implications for elimination strategies |
Prof L Birkholtz, Dr J Raman, Prof T Bousema |
| Mr AB Mapossa | PhD, Chemical Engineering | Thesis | Slow-release of mosquito repellents from microporous polyolefin strands | Prof WW Focke |
| Mr M Mpofu | PhD, Environmental Health | Thesis | Effectiveness of community larval source management (LSM) as an additional vector control intervention for malaria elimination |
Prof C de Jager, Dr K Mudambo |
| Mr AEJ Sitoe | PhD, Chemical Engineering | Thesis | Controlled-Release of mosquito repellents from microporous polymer strands | Prof WW Focke |
| Ms M van der Watt | PhD, Biochemistry | Thesis | Exploring the kinase inhibitor chemical space for dual active and gametocyte-focused antimalarials | Prof L Birkholtz, Dr J Niemand |
| Ms EA Misiani | MSc, Public Health | Dissertation | An assessment of malaria vector control and staff workloads in South Africa: implications for malaria elimination | Prof A Beke, Prof C de Jager |
| Ms Z Mkatshane | MSc, Plant and Soil Science | Dissertation | Antimicrobial and antimalarial activity of Tabernaemontana elegans Stapf. (Apocynaceae) | Dr MJ Bapela, Dr TE Tshikalange |
| Ms N Sibiya | MSc, Environmental Health | Dissertation | Sperm chromatin integrity is pesticide exposed | Dr N Aneck-Hahn, Prof C de Jager |
| Ms S da Rocha | BSc Honours, Biochemistry | Research report | Investigating the essentiality of putative mitochondrial pyruvate carriers within the intraerythrocytic stages of Plasmodium falciparum parasites | Dr J Niemand |
| Mr H Langeveld | BSc Honours, Biochemistry | Research report | Targeted gene disruption of novel putative kinases involved in the cell cycle of Plasmodium falciparum parasites | Prof L Birkholtz |
| Ms R Mofokeng | BSc Honours, Biochemistry | Research report | Investigating the role of putative amino acid transporters during the Plasmodium falciparum intra-erythrocytic stages | Dr J Niemand |
| Mr D Opperman | BSc Honours, Biochemistry | Research report | Epi-drugs kill asexual Plasmodium falciparum parasites through global changes in histone acetylation status and confer transmission blocking | Prof L Birkholtz |
| Ms J Tempies | BSc Honours, Biochemistry | Research report | Exploring a novel family of putative RNA binding proteins potentially driving asexual proliferation in Plasmodium falciparum | Prof L Birkholtz |
| Ms A Warima | BSc Honours, Biochemistry | Research report | Characterisation of a recombinant S-adenosylmethionine decarboxylase mutant as a novel drug target in the malaria parasite, Plasmodium falciparum | Dr D Coertzen, Prof L Birkholtz |
| Student | Degree | Type | Title | Supervisors |
| Ms N Coetzee | PhD, Biochemistry | Thesis | Sexual differentiation of malaria parasites is controlled by unique epigenomic and proteomic cascades as revealed by comparative functional genome analysis |
Prof L Birkholtz |
| Ms J Reader | PhD, Biochemistry | Thesis | Interrogation of the chemo- therapeutic and transmission-blocking abilities of metallodrugs against malaria parasites |
Prof L Birkholtz, Dr D Meyer |
| Ms T Adebayo-Ojo | MSc, Public Health | Dissertation | Indoor Residual Spraying (IRS) and Climate Variability on Malaria Burden in Vhembe district, Limpopo Province, South Africa from 2005 - 2015 | Prof MS Bornman, Prof J Gaudart |
| Ms DL Kouemo | MSc, Pharmacology | Dissertation | Assessing the in vitro efficacy of in silico designed compounds targeting the malarial Qi site of cytochrome bc1 | Prof L Birkholtz, Prof AD Cromarty, Dr BA Stander |
| Mr TP Madzorera | MSc, Chemical Engineering | Dissertation | A slow-release organophosphate-filled trilayer polyolefin film | Prof WW Focke |
| Ms M Naude | MSc, Biochemistry | Dissertation | Dynamic bioinformatics and isotopic evaluation of the permeome of intraerythrocytic Plasmodium falciparum parasites | Prof L Birkholtz, Dr J Niemand |
| Mr AP Roodt | MSc, Chemistry | Dissertation | A new sampling method for human skin volatile analysis by comprehensive gas chromatography and mass spectrometry | Prof E Rohwer, Prof A Stoltz, Dr Y Naude |
| Ms H von Grüning | MSc, Biochemistry (Cum Laude) | Dissertation | CRISPR/Cas9 mediated deletion of genes encoding putative cell cycle regulators in Plasmodium falciparum | Prof L Birkholtz |
| DF Botha | BSc Honours, Biochemistry | Research report | Functional evaluation of RNA binding proteins in regulating re-initiation of the cell cycle after cell cycle arrest in Plasmodium falciparum | Prof L Birkholtz, Dr J Niemand |
| M Freeman | BSc Honours, Biochemistry | Research report | Creating a sex specific Plasmodium falciparum gametocyte transmission blocking assay by reverse transcriptase qPCR | Dr BK Brider, Prof L Birkholtz |
| Ms MK Leshabane | BSc Honours, Biochemistry | Research report | Investigation of the possible anti-plasmodial activity of DNA gyrase inhibitors against asexual and sexual intra erythrocytic stages of Plasmodium falciparum | Prof L Birkholtz, Dr J Niemand |
| D Moonasamy | BSc Honours, Biochemistry | Research report | Detection and quantification of oxidative stress on multiple stages of Plasmodium falciparum parasites | Dr D Coertzen, Prof L Birkholtz |
| Ms M Robbertse | BSc Honours, Biochemistry | Research report | Localization of putative amino acid transporters in Plasmodium falciparum using selection linked integration | Dr J Niemand, Prof L Birkholtz |
| Ms M Ryder | BSc Honours, Biochemistry | Research report | Targeted gene disruption of a putative Plasmodium falciparum ORC3 cell cycle modulator | Dr J Niemand, Prof L Birkholtz |
| Ms F Shingange | BSc Honours, Biochemistry | Research report | Validation of drug affinity responsive target stability assay in the identification of antimalarial drugs biological targets in asexual blood stage Plasmodium falciparum | Prof L Birkholtz, Dr P Moyo |
| Student | Degree | Type | Title | Supervisors |
| Ms H Izadi | PhD, Chemical Engineering | Thesis | A novel pseudo-azeotrope mosquito repellent mixture | Prof WW Focke, Dr J Pretorius |
| Mr P Moyo | PhD, Biochemistry | Thesis | Natural products as potent and pan-reactive antimalarial agents: Discovery, isolation and biochemical characterisation |
Prof L Birkholtz, Prof AI Louw, Prof VJ Maharaj,Prof JN Eloff |
| Mr EW Besaans | MSc, Biochemistry | Dissertation | Synthesis, structure-activity relationships and biological evaluation of optimised terminally alkylated (bis) urea and (bis)thiourea polyamine analogues as anti-plasmodial agents | Prof L Birkholtz, Dr N October |
| Ms J Connacher | MSc, Biochemistry (Cum Laude) | Dissertation | Deconvoluting drug mode-of-action: Transcriptomic evaluation of novel clinical lead antimalarials | Prof L Birkholtz |
| Ms JS Duvenhage | MSc, Biochemistry (Cum Laude) | Dissertation | Radiolabeled antibodies as detection tool for malaria parasite (Plasmodium falciparum 3D7) - infected human erythrocytes | Prof L Birkholtz, Prof JR Zeevaart |
| Ms DMA Matlebjane | MSc, Biochemistry | Dissertation | In vitro efficacy assessment of targeted antimalarial drugs synthesized following in silico design | Prof AD Cromarty, Prof L Birkholtz, Dr BA Stander |
| Ms ME Dilebo | BSc Honours, Biochemistry | Research report | Determination of cellular oxidative stress generation because of artemisinins and methylene blue treatment in intracellular malaria parasites, Plasmodium falciparum | Prof L Birkholtz, Dr D Coertzen |
| Ms D Joubert | BSc Honours, Biochemistry | Research report | Investigating polyamine agents as novel transmission blocking antimalarial drugs on the gamete forms of the Plasmodium falciparum parasites | Prof L Birkholtz, Dr BK Brider |
| Ms T Khan | BSc Honours, Biochemistry | Research report | Development of an in-house phenotype microarray plate for analysis of asexual Plasmodium falciparum parasites | Dr J Niemand, Prof L Birkholtz |
| Ms SM Maboane | BSc Honours, Biochemistry | Research report | The phenotypic characterization of carbohydrate and amino acid metabolism use in the Dd2 strain of Plasmodium falciparum parasites | Dr J Niemand, Prof L Birkholtz |
| JJM Marais | BSc Honours, Biochemistry | Research report | Vector construction for targeted CRISPR-Cas9 mediated gene disruption of an epigenetic gene regular PfGCN5 in Plasmodium falciparum parasites | Prof L Birkholtz |
| Ms A van Heerden | BSc Honours, Biochemistry | Research report | Optimisation of high-throughput screening platform for antiplasmodial drug activity determination against asexual Plasmodium falciparum stages | Prof L Birkholtz, Dr J Niemand |
| Student | Degree | Type | Title | Supervisors |
| Mr A Adeola | PhD, Geography | Thesis | Application of remotely sensed environmental variables for predicting malaria cases in Nkomazi municipality, South Africa | Dr OJ Botai, Dr JM Olwoch |
| Ms J Bapela | PhD, Plant and Soil Science | Thesis | NMR-based metabolomic study of medicinal plants used against malaria and the isolation of bioactive alkaloids | Prof M Meyer |
| Mr DK Komen | PhD, Geography | Thesis | Impact of climate on health: A specific focus on Malaria in South Africa’s Limpopo Province |
Dr JM Olwoch, Dr OJ Botai |
| Mr SM Patrick | PhD, Environmental Health | Thesis | Effects of in utero-, lactational- and direct exposure to selected endocrine disrupting chemicals on the rat male reproductive system | Prof C de Jager, Prof MS Bornman, Prof A Joubert |
| Ms C Pillay | MSc, Pharmacology | Dissertation | Characterisation of P. falciparum proteins expressed on infected red blood cell surfaces as potential drug targets for severe malaria therapy | Prof AD Cromarty |
| Ms JS Duvenhage | BSc Honours, Biochemistry | Mini-dissertation | In vitro cultivation of Plasmodium ovale and gametocyte producing strains of Plasmodium falciparum | Prof L Birkholtz |
| Ms C Abrie | BSc Honours, Biochemistry | Research report | Investigating antiplasmodial potential of (bis) urea and (bis)thiourea polyamine analogues on the gamete form of Plasmodium falciparum parasites | Prof L Birkholtz, Dr J Niemand |
| Mr C Breedt | BSc Honours, Biochemistry | Research report | An evaluation of the gametocytocidal activity of natural product compound against the P. falciparum parasite | Prof L Birkholtz, Dr J Niemand |
| Ms D Henn | BSc Honours, Biochemistry | Research report | Drug target deconvolution of antiplasmodial compounds using drug affinity responsive target stability on the sexual and asexual stages of P. falciparum parasites | Prof L Birkholtz, Dr J Niemand |
| Ms T Makhanthisa | BSc Honours, Biochemistry | Research report | Evaluation of the prevalence of CYP 2D6 mutation prevalence in the population of Vhembe District, Limpopo Province | Prof L Birkholtz, Dr J Niemand |
| Ms N Mmekwa | BSc Honours, Biochemistry | Research report | Evaluation of the effect of epigenetic modifying drugs during gametocyto-genesis of the Plasmodium falciparum parasite | Prof L Birkholtz, Dr J Niemand |
| Ms G Weidemann | BSc Honours, Biochemistry | Research report | Investigation of differential drug responses in different P. falciparum parasite life cycle stages | Prof L Birkholtz, Dr J Niemand |
| Student | Degree | Type | Title | Supervisors |
| Ms C Coertzen | PhD, Biochemistry | Thesis | Structural and functional characterisation of AdoMetDC in Plasmodium falciparum |
Prof L Birkholtz, Prof AI Louw |
| Ms I Roussouw | PhD, Genetics | Thesis | Transcriptional response to the herbicide-derived compound A51B1C1_1 in the zoonotic parasite - Babesia divergens | Dr C Maritz-Olivier, Prof L Birkholtz |
| Mr M Sibanda | PhD, Chemical Engineering | Thesis | Polyolefin copolymers as controlled release devices for insecticides and repellents | Prof WW Focke |
| Mr MU Akhtar | MSc, Chemical Engineering | Dissertation | Towards controlled release of a natural mosquito repellent from polymer matrices | Prof WW Focke |
| Ms B Barnard | MSc, Biochemistry (Cum Laude) | Dissertation | Biochemical analysis of lysine-specific demethylases in malaria parasites | Prof L Birkholtz |
| Ms K Baron | MSc, Pharmacology (Cum Laude) | Dissertation | Enzymatic and chemical modifications of erythrocyte surface antigens to identify P. falciparum merozoite binding sites | Prof AD Cromarty |
| Ms N Coetzee | MSc, Biochemistry (Cum Laude) | Dissertation | Detailed and comprehensive description of the histone code in Plasmodium falciparum asexual and gametocyte stages through mass spectrometry based proteomics | Prof L Birkholtz |
| Ms C Pillay | MSc, Pharmacology | Dissertation | Characterisation of P. falciparum proteins expressed on infected red blood cell surfaces as potential drug targets for severe malaria therapy | Prof AD Cromarty |
| Ms D Steyn | MSc, Pharmacology | Dissertation | Mechanisms of potential novel antimalarials and proteomics of Plasmodium falciparum resistance | Prof AD Cromarty |
| Ms R van Biljon | MSc, Biochemistry (Cum Laude) | Dissertation | Probing the unusual cell cycle of Plasmodium falciparum using DFMO, a cytostatic life cycle stage-specific inhibitor | Prof L Birkholtz, Dr J Niemand |
| Mr S Kneitz | BSc Honours, Biochemistry (Cum Laude) | Research report | Identification of the biochemical target/s of novel antimalarial compounds with DARTS technology | Prof L Birkholtz |
| A Marevati | BSc Honours, Biochemistry | Research report | Characterisation of a novel S-adenosylmethionine decarboxylase mutant for structure based drug discovery in the malaria parasite, Plasmodium falciparum | Prof L Birkholtz |
| Ms A Ramjan | BSc Honours, Biochemistry (Cum Laude) | Research report | Validation of histone deacetylase inhibitors as novel antiplasmodial agents | Prof L Birkholtz, Dr J Niemand |
| Student | Degree | Type | Title | Supervisors |
| Ms BK Verlinden | PhD, Biochemistry | Thesis | Polyamine analogues exhibit an antimalarial effect through targeting Plasmodium falciparum cell cycle |
Prof L Birkholtz |
| Ms M de Beer | MSc, Biochemistry | Dissertation | In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs | Prof L Birkholtz |
| Ms N Ismail | MSc, Biochemistry | Dissertation | Inhibition of the histone deacetylase family as a drug target in the human malaria parasite, P. falciparum | Prof L Birkholtz |
| Mr M Szolkiewicz | MSc, Biochemistry | Dissertation | Homology-based in silico identification of putative protein-ligand interactions in the malaria parasite | Prof F Joubert |
| Ms TB Bawuba | MPH, Public Health | Mini-dissertation | Assessing the impact of indoor residual spraying (IRS) on Malaria Morbidity in Northern Uganda | Prof A Beke |
| Ms N Ramalwa | MPH, Public Health | Mini-dissertation | Insecticide susceptibility analysis of Anopheles gambiae complex in Vlakbult, Mphumalanga 2012/13 | Prof C de Jager |
| Mr E Besaans | BSc Honours, Biochemistry | Research report | Novel polyamine trimer analogues as potential transport inhibitors in P. falciparum | Prof L Birkholtz |
| Ms JS Duvenhage | BSc Honours, Biochemistry | Research report | In vitro cultivation of Plasmodium ovale and gametocyte producing strains of Plasmodium falciparum | Prof L Birkholtz |
| Mr Y Mbous | BSc Honours, Biochemistry | Research report | Characterising the link between polyamine metabolism and redox regulation in Plasmodium falciparum, BSc Hons mini-dissertation | Prof L Birkholtz, Prof AI Louw |
| VE Nkuna | Diploma in Public Health Medicine | Research report | Community knowledge, attitudes and perceptions about malaria prevention in rural area in Mopani District of Limpopo Province, South Africa | Prof C de Jager |
| Ms RM Ramathole | Diploma in Public Health | Research report | Integrated Vector Management for Malaria | Prof C de Jager |
| Ms H Roos | Diploma in Occupational Medicine and Health | Research report | HRA of a chemical Malaria vector control programme implemented at a large temporary construction camp site in Palma, Mozambique | Prof C de Jager |
| Student | Degree | Type | Title | Supervisors |
| Ms K Clarke | PhD, Biochemistry | Thesis | The effect of polyamine depletion on the transcriptome of Plasmodium falciparum |
Prof L Birkholtz, Prof AI Louw |
| Ms C Rossouw | PhD, Biochemistry | Thesis | Investigations of liver stage functional genomics of Plasmodium falciparum | Prof L Birkholtz, D Mancama, H Hoppe, S Moolman |
| Ms C Griffiths | MSc, Biochemistry (Cum Laude) | Dissertation | The construction of high-resolution probability maps for the study of gene expression and regulation in Plasmodium falciparum | Prof L Birkholtz, M Mhlanga |
| Mr S Reekstring | MSc, Biochemistry | Dissertation | Structure-based drug discovery for malarial vit B6 and polyamine drug targets and evaluation thereof by functional genomics | Prof L Birkholtz, Prof AI Louw, C. Wrenger |
| Mr J Reynolds | MSc, Biochemistry | Dissertation | Structure-functional elucidations of ODC as antimalarial drug target | Prof L Birkholtz, Prof AI Louw |
| Ms N Coetzee | BSc Honours, Biochemistry (Cum Laude) | Research report | Novel antimalarial agents targeting Plasmodium falciparum spermidine synthase by way of rational-based drug design | Prof L Birkholtz, T van Brummelen |
| Mr de la Rey | BSc Honours, Biochemistry | Research report | Identifying lead compounds for Plasmodium falciparum S-Adenosyl methionine Decarboxylase | Prof L Birkholtz |
| Ms N Gouws | BSc Honours, Biochemistry | Research report | Investigating the effect of quinoline antimalarials on Plasmodium falciparum polyamine metabolism | Prof L Birkholtz |
| Ms R van Biljon | BSc Honours, Biochemistry (Cum Laude) | Research report | Investigations of the inhibitory effect of 1,4-diamino-2-butanone of the Plasmodium falciparum parasite | Prof L Birkholtz |
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