Dr A Pretorius

Extraordinary Lecturer: Immunology/Biochemistry
Senior Researcher: ARC-OVI

BSc (Biochemistry) MSc (Biochemistry) PhD (Veterinary tropical diseases)

Dr Alri Pretorius

Office
Room 22
Molecular Biology Building 35
Onderstepoort Veterinary Institute

Postal address
ARC-Onderstepoort Veterinary Research
Private Bag X05
Onderstepoort 0110
South Africa

Professional and academic experience

  • 22 years experience as researcher
  • 8 years experience as extraordinary lecturer

Professional memberships

SAVC member

Subjects taught at undergraduate and postgraduate levels

Training postgrad students in veterinary Immunology

Research interests

  • Recombinant vaccine development, veterinary and large animal cellular immunology and immune transcriptomics, Molecular biology biochemistry, epidemiology

Collaboration

International:

  1. LEAP-AGRI: CIRAD(France), CIRDES (Burkina Faso) and IBET (Portugal) – Inactivated heartwater vaccine project
  2. IDRC: TIBA (USA) and Mordun (UK) – Foot-and-mouth disease vaccine project
  3. H2020-DEFEND project: IDVET- Lumpy skin disease project

National:

  1. OPB – Attenuated heartwater project and a AHSV project
  2. UP- LEAP-Agri - inactivated heartwater vaccine project

Postgraduate students

PhD students:

  1. Z LUKANJI: PhD (Veterinary Science). Assessment of an inactivated multivalent heartwater vaccine under field conditions. Started 2018
  2. FE FABER: PhD (Veterinary Science). Identification of cytotoxic T lymphocyte and CD4+ T cell epitopes of African horse sickness virus serotype 4, in vitro. Started 2017
  3. N THEMA: PhD (Veterinary Science). Identification and characterisation of Ehrlichia ruminantium vaccine candidate epitopes. Completed 2018
  4. MA TJALE: PhD (Veterinary Science). Transcriptome analysis of E. ruminantium at the tick bite site and during the developmental stages in cell culture. Completed 2017
  5. T NEFEFE: PhD (Veterinary Science). Determination of the sheep innate and adaptive immune transcriptome after infection with Ehrlichia ruminantium. Completed 2016
  6. SI SABATJANE: PhD (Veterinary tropical diseases). Developing an optimised recombinant vaccine for heartwater. Completed 2010.

MSc students:

  1. MABETLELA FM MSc (Veterinary Science). Identification of African Swine Fever Virus proteins that activates T-cell immune responses Completed 2019
  2. C RASELABE. MSc (Veterinary Science). In vitro characterisation of the cellular immune response induced by African Swine Fever Virus proteins p30, P54 and p72. Completed 2017.
  3. TA NGOEPE: MSc (Veterinary Science). Identification and characterisation of T and B cell epitopes of E. ruminantium ORF 2510. Completed 2017
  4. RM SMITH: MSc (Veterinary Science). Identification of Ehrlichia ruminantium vaccine candidate epitopes of Erum5400, -8050 and -5270. Completed 2016
  5. LA SON: MSc (Veterinary Science). Identification of Ehrlichia ruminantium cytotoxic lymphocyte epitopes and CD4 T cell epitopes of Erum 2550, 2580 and 2590. Completed 2016 Cum laude.
  6. EM MATHEBULA. MSc (Veterinary Science). Identifying B-cell epitopes of African horsesickness virus in immune horses. Completed 2016. Cum laude
  7. N THEMA: MSc (Veterinary tropical diseases). Towards a recombinant vaccine for heartwater. Completed 2008.
  8. FE FABER: MSc (Veterinary tropical diseases). The identification of Ehrlichia ruminantium membrane-associated proteins that induce cellular immune responses in vitro. Completed 2010.
  9. N TSHIKHUDO: MSc (Veterinary tropical diseases) - Biodegradable microspheres as a single dose delivery system for Ehrlichia ruminantium vaccines. Completed 2009.

Research output/publications

  • 18 publications in peer-reviewed or refereed journals
  • 1 book chapters
  • 18 congress proceedings
  • 6 full-length conference papers/keynote addresses
  • 5 non-refereed publications
  • 3 technical reports

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