Dr Maria Karsas attended the combined 18th International Congress of Endocrinology (ICE) and the 53rd Annual Society for Endocrinology, Metabolism and Diabetes of South Africa (SEMDSA) Conference in Cape Town from 1-4 December 2018. The Paediatric and Adolescent Endocrinology & Diabetes Society – South Africa (PAEDS-SA), of which Dr Karsas is a member, annual meeting was also held during the conference. Dr Karsas presented a poster at the conference entitled: An Unusual Case of Ambiguous Genitalia. This was a wonderful opportunity to show case our ability to make a diagnosis of a rare condition, namely Smith-Lemli-Opitz syndrome. Attendance of this conference was a fantastic opportunity for exposure to both local and international experts in the field of both adult and paediatric endocrinology.  Knowledge was gained in regards to advancements in diagnostics as well as new management practices. Overall, it was a memorable and knowledge rich experience that will greatly aid our approach to paediatric endocrinology.