Publications: Molecular Endocrinology

Name: Prof Tahir Pillay

e-mail: [email protected]

Tel: 012-319-2155

 

Publications of the past 5 years:

Original publications in ISI accredited journals:

  1. Pillay TS (2017) The Journal of Clinical Pathology at 70: Who's citing who? Where has the journal been cited? J Clinical Pathology. 2017 Oct;70(10):817-818. doi: 10.1136/jclinpath-2017-20475

 

  1. Pema A, Kiabilua O, Pillay TS (2017) Demand management by electronic gatekeeping of test requests does not influence requesting behaviour or save costs dramatically. Annals of Clinical Biochemistry 2017 Jan 1:4563217707980. doi: 10.1177/0004563217707980. [Epub ahead of print]

 

  1. Chale-Matsau B, van Niekerk C, Kemp T, Pillay TS (2017) Discordant calcium and parathyroid hormone with presumed epileptic seizures Clinical Chemistry (in press)

 

  1. Satekge T, Kiabilua O, Pillay K, van Biljon G, Pillay TS (2017) A toddler with anasarca caused by congenital nephrotic syndrome. e-Journal IFCC ( in press)

 

  1. Islam MA, Pillay TS (2017) Identification of promising DNA GyrB inhibitors for Tuberculosis using pharmacophore-based virtual screening, molecular docking and molecular dynamics studies. Chemical Biology and Drug design Chemical Biology and Drug Design 2017 Aug;90(2):282-296 doi: 10.1111/cbdd.12949.

 

  1. Pillay TS (2017) The new MedTech Europe directive: implications for educational activities in pathology and laboratory medicine. Journal of Clinical Pathology 2017 Mar;70(3):185-186. doi: 10.1136

 

  1. Pillay TS (2017) 70 years of the Journal of Clinical Pathology: Quo vadis? Journal of Clinical Pathology 2017 Feb;70(2):93. doi: 10.1136

 

  1. Reynolds TM, Pillay TS. Donald Rumsfeld and point-of-care testing (POCT): the problem of unknown unknowns-venous blood and glucose oxidase-based test strips. Horm Metab Res. 2016 Nov 3. J Clin Pathol. 2016 Oct;69(10):839-40. doi: 10.1136/jclinpath-2016-203931.

 

  1. Ross IL, Lacerda M, Pillay TS, Blom DJ, Johannsson G, Dave JA, Levitt NS, Haarburger D, van der Walt JS. Salivary Cortisol and Cortisone do not appear to be Useful Biomarkers for Monitoring Hydrocortisone Replacement in Addison's Disease. Horm Metab Res. 2016 Nov 3. [Epub ahead of print].

 

  1. Yako YY, Madubedube JH, Kengne AP, Erasmus RT, Pillay TS, Matsha TE. Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa. Afr Health Sci. 2015 Dec;15(4):1149-60.

 

  1. Islam M.A., Bhayye S., Adeniyi A.A., Soliman M.E.S., Pillay T.S.. (2016) Diabetes Mellitus caused by  mutations in human insulin: Analysis of impaired receptor binding of insulins Wakayama, Los Angeles and Chicago using Pharmacoinformatics Journal of Biomolecular Structure and Dynamics 2016 Apr 14:1-14. [Epub ahead of print] DOI:10.1080/07391102.2016.1160258.

 

  1. Islam MA, Pillay T.S. (2016) Simplified Molecular Input Line Entry System-based descriptors in QSAR modelling for HIV-protease inhibitors Chemometrics and Intelligent Laboratory Systems (in press).

 

  1. Islam MA, Pillay  T.S. (2016) Structural requirements for potential HIV-integrase inhibitors identified using pharmacophore-based virtual screening and molecular dynamics studies  Molecular BioSystems, Feb 23;12(3):982-93, DOI: 10.1039/C5MB00767D.

 

  1. Oosthuizen N.M.O; Olivier J., Martins J., Schutte S., Pillay T.S.  (2016) Red-brown urine in a patient with chronic HIV-infection and quadriparesis. Clinical Chemistry Sep;62(9):1181-4.

 

  1. Islam M.A., Patel D.A., Rathod S.G., Chunarkar P., Pillay T.S. (2016) Identification of Structural Requirement of Estrogen Receptor Modulators using Pharmacoinformatics Techniques for Application to Estrogen Therapy. Medicinal Chemistry Research (in press).

 

  1. Martins J, Olorunju SA, Murray LM, Pillay TS. Comparison of equations for the calculation of LDL-cholesterol in hospitalized patients. Clin Chim Acta. 2015 Apr 15;444:137-42.

 

  1. Islam MA, Pillay TS. Exploration of the structural requirements of HIV-protease inhibitors using pharmacophore, virtual screening and molecular docking approaches for lead identification. J Mol Graph Model. 2015 Mar;56:20-30.

 

  1. Stanfliet JC, Locketz M, Berman P, Pillay TS. Evaluation of the utility of serum prolidase as a marker for liver fibrosis. J Clin Lab Anal. 2015 May;29(3):208-13

 

  1. Omar F, Dave JA, King JA, Levitt N, Pillay TS High molecular weight (HMW): Total adiponectin ration is low in HIV-infected women receiving protease inhibitors.   BMC Clinical Pathology (in press)

 

  1. Why are we still measuring red cell folate instead of just serum folate? Pillay TS, Oosthuizen NM. J Clin Pathol. 2014 Apr;67(4):289. doi: 10.1136/jclinpath-2013-202086. Epub 2013 Dec 27.

 

Review articles in ISI accredited journals:

  1. Moodley N, Mnxganga U, Turzyniecka M, Pillay TS: Historical perspectives in clinical pathology: a history of point-of-care glucose measurement. Moodley N, Mnxganga U, Turzyniecka M, Pillay TS J. Clin Pathol  (2015) Apr;68(4):258-64

 

Book chapters:

  1. Pillay TS (sole author); Interactive Mathematics for Laboratory medicine  (interactive iBook; Apple Itunes store) Published September 2015

 

Chapters authored:

  1. Basic calculations
  2. Basic descriptive statistics
  3. Receiver-operator curves and diagnostic tests
  4. Spectrophotometry
  5. Calculations in genetics
  6. Using Chi-squared tests
  7. Half-life calculations
  8. Pharmacokinetic equations
  9. Baye’s Theorem
  10. Sensitivity, Specificity and Predictive values
  11. Z-scores
  12. Reference change values
  13. Uncertainty of measurement
  14. Comparison of two methods

 

  1. Pillay TS  & Erasmus R, editors

Practical Clinical Chemistry: core concepts –a training manual (interactive iBook; Apple Itunes store) (to appear in 2014)

Chapters authored:

  1. Chapter 1: Basic laboratory mathematics and practice:  dilutions and standard curves; pipetting
  2. Chapter 2: Plotting a standard curve: using a dye-binding  protein assay as an example
  3. Chapter 3: Basic enzyme kinetics: comparison of an endpoint  and a kinetic method
  4. Chapter 9: Analysis of a macroenzyme using gel filtration  or PEG precipitation

 

Conference proceedings:

  1. American Association of Clinical Chemistry Annual Meeting, San Diego, July 2017; AACC university workshop “ Challenges at the clinical laboratory interface; “  Investigation of interferences in clinical chemistry and general endocrine testing”

 

  1. EuromedLab Athens, June 2017; Oral presentations: “Demand management and Electronic gatekeeping in clinical laboratory testing. Invited speaker at IFCC CPD symposium “ Electronic laboratory resources for health professionals.”

 

  1. IFCC Worldlab Durban 2017, 22-25 October 2017; Invited speaker at ACP symposium and Risk Management Symposium

 

  1. International Congress of Paediatric laboratory medicine, Durban; Chale-Matsau B; Pillay T.S. “An unusual cause of hyperammonaemia in an infant”.

 

  1. Keynote Speaker- “Understanding Cell Communication in health and disease”  International Cell Signalling Conference, Kuala Terengganu, Malaysia ( July 2017)

 

  1. Pillay T.S., Plenary presentation “Digital publishing in academia: implications for clinical chemistry “ (2016); IFCC General conference-Madrid, 18-21 March 2016.

 

  1. P5 conference on 'Leveraging Point of Care Testing and Personalised Medicine to Advance Healthcare'; Plenary presentation; “Nanobodies: new diagnostic probes for Point of Care Testing” Cape Town; 23-25 March 2016.

 

  1. SEMDSA (Society for Endocrinology, Metabolism and Diabetes, South Africa) workshop convenor and chair, SEMDSA meeting; “The interface between endocrinology and laboratory medicine- the hitchhikers guide” 14-16 April 2016; Cape Town.

 

  1. ACB Focus meeting; Poster presentation “Standing on the shoulders of giants: milestones in the history of ligand assay development”; Warwick UK 18-21 April 2016.

 

  1. American Association of Clinical Chemistry, Philadelphia; Poster presentation “Validation of the calcium correction formula using serum total calcium, albumin, corrected calcium and ionized calcium” Philadelphia 31 July -4 Aug 2016.

 

  1. UEMS-EFLM(European Federation of Laboratory Medicine) meeting- “Laboratory Medicine at the Clinical Interface” ; 21-24 September 2016; Warsaw ; Oral presentations: “Digital publishing in clinical chemistry and laboratory medicine”; “New and old formulas for the calculation of LDL Cholesterol: a re-evaluation.”

 

  1. Pillay T.S. Digital publishing in academia: implications for clinical chemistry (2015) Clin Chem Lab Med 2015 53: Special Suppl S559 (EuromedLab Paris 2015)

 

  1. Chale-Matsau B., Pillay T.S. Recurrent Seizures in a Child due to hypoketotic hypoglycaemia(2015) Clin Chem Lab Med 2015 53: Special Suppl S580 (EuromedLab Paris 2015)

Kenyan Association of Clinical Pathologists Annual meeting, Risk management in the Clinical Laboratory, October 2015

 

  1. Congress of the Latin American Congress of Clinical Biology Societies, Quito, Ecuador, September 2015
  1. Pillay T.S.; Critical values in Paediatrics
  2. Pillay T.S.; Risk management in the Clinical Laboratory

 

  1. Royal College of Pathologists/COPECSA Lab skills Africa Workshop, Nairobi, Kenya, 18-22 Jan 2014; "Quality control and assurance in resource-challenged environments."

 

  1. Royal College of Pathologists/COPECSA Lab skills Africa Workshop, Moshi, Tanzania, 14-18 Feb 2014; "The art of negotiation:  techniques and exercises."
  2.  
  3. IFCC Worldlab 2014 , Istanbul, June 2014; J. Martins, L. Murray, Olurunju S, Pillay TS “Evaluation of equations for LDL-C calculations in hospitalised patients”

 

  1. American Association of Clinical Chemistry Annual Meeting, Chicago, July 2014 : J. Martins, L. Murray, Olurunju S, Pillay TS “Comparison of equations for LDL-C calculations in hospitalised patients”

 

Other:

Media articles/interviews/etc.:

Sunday Tribune, 22 Jan 2017; TS Pillay “ Challenges facing graduates of foreign medical schools returning to South Africa”;

NRF rated members of the group:

T.S. Pillay C3

Awards/distinctions of the past 5 years:

  1. Senior Research Award, South African Association for Clinical Biochemistry and Laboratory Medicine, 2013 (for outstanding scientific achievement)
  2. Elected to the Academy of Science of South Africa in recognition for scientific achievement and contributions
  3. Awarded a Higher Education Leadership Management Fellowship in 2013. I was one of two people from the University of Pretoria awarded this fellowship from Higher Education South Africa to attend a two-week workshop on leadership management in October and December 2013
  4. Nominated for the IFCC Distinguished Education award in 2017 by the South African Association for Clinical Biochemistry and Laboratory for developing innovative teaching materials in Clinical Chemistry

 

 

updated 22/05/2019

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