Publications: Antimicrobial resistance and sexually transmitted infections

Name: Dr MM Kock

e-mail: [email protected]

Tel: 012 319 2325

Cell: 072 215 2544

 

Publications of the past 5 years:

Original publications in ISI accredited journals:

  1. Redelinghuys, M.J., Ehlers, M.M., Dreyer, A.W., Lombaard, H.A. and Kock, M.M. (2014) Antimicrobial susceptibilities of Ureaplasma species and Mycoplasma hominis in pregnant women. BMC Infectious Diseases 14: 171 (IF=3.12)

 

  1. Strasheim W, Kock MM, Ueckermann V, Hoosien E, Dreyer AW and Ehlers MM (2015) Surveillance of catheter-related infections: the supplementary role of the microbiology laboratory.  BMC Infectious Diseases 15:5 (IF=2.56)

 

  1. Redelinghuys MJ, Ehlers MM, Dreyer AW, Lombaard H, Olorunju SAS and Kock MM (2015) A cross-sectional study on the relationship of age, gestational age and HIV infection to bacterial vaginosis and genital mycoplasma infection. BMJ Open 5:e008530. doi:10.1136/bmjopen-2015-008530 (IF: 2.271)

 

  1. Schmidt T, Kock MM and Ehlers MM (2015) Diversity and antimicrobial susceptibility profiling of staphylococci isolated from bovine mastitis cases and close human contacts.  Journal of Dairy Sciences 98:6256–6269 (IF: 2.5).

 

  1. Van der Eem L, Dubbink JH, Struthers HE, McIntyre JA, Ouburg S, Morre SA,  Kock MM, Peters RPH (2016) Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women. Tropical Medicine and International Health Epub ahead of print: doi: 10.1111/tmi.12742. (IF=2.329)

 

  1. Redelinghuys MJ, Ehlers MM, Bezuidenhoudt JE, Becker PJ, Kock MM (2017) Molecular quantification of Atopobium vaginae and Gardnerella vaginalis in pregnant women. Sexually Transmitted Infections 93(6): 410-415 (IF: 3.015).

 

  1. Schmidt T, Kock MM, Ehlers MM (2017) Molecular characterization of Staphylococcus aureus isolated from bovine mastitis and close human contacts in South African dairy herds: genetic diversity and inter-species host transmission. Frontiers in Microbiology 8:511. doi: 10.3389/fmicb.2017.00511 (IF=4.165).

 

  1. Peters RP, Doyle R, Redelinghuys S, McIntyre JA, Verjans GM, Breuer J, Kock MM (2017) Genital Chlamydia trachomatis biovar L2 infection in South African women. Emerging Infectious Diseases 23(11):1913-1915 (IF: 8.22).

 

  1. Senamela T, Kock M, Becker P, Potgieter JC (2017) Detection of the Janus kinase 2 V617F mutation using a locked nucleic acid real-time PCR assay. Accepted in African Laboratory Journal of Medicine.

 

  1. Peters R, de Vos L, Maduna L, Mudau M, Klausner J, Kock M, Medina-Marino A (2017) Laboratory validation of Xpert® CT/NG and TV testing as performed by nurses at three primary healthcare facilities in South Africa. Accepted in Journal of Clinical Microbiology (IF=3.712)

 

  1. Price CM, Peters RPH, Steyn J, Mudau M, Olivier D, De Vos L, Morikawa E, Kock MM, Medina-Marino A, Klausner JD (2017) Prevalence and detection of Trichomonas vaginalis in human immunodeficiency virus-infected pregnant women. Accepted in Sexually Transmitted Diseases (IF=2.968)

 

  1. Price CM, Peters RPH, Steyn J, Mudau M, Olivier D, De Vos L, Morikawa E, Kock MM, Medina-Marino A, Klausner JD (2018) Prevalence and detection of Trichomonas vaginalis in human immunodeficiency virus-infected pregnant women. Sexually Transmitted Diseases 45(5):332-336. doi: 10.1097/OLQ.0000000000000756 (IF=2.968).

 

  1. Ehlers MM, Strasheim W, Lowe M, Ueckermann V, Kock MM (2018) Molecular epidemiology of Staphylococcus epidermidis implicated in catheter-related bloodstream infections at an academic hospital in Pretoria, South Africa. Frontiers in Microbiology 9:417. doi: 10.3389/fmicb.2018.00417 (IF=4.076)

 

  1. Senamela T, Kock M, Becker P, Potgieter JC (2018) Detection of the Janus kinase 2 V617F mutation using a locked nucleic acid real-time PCR assay. African Laboratory Journal of Medicine 7(1): a658. https://doi. org/10.4102/ajlm.v7i1.658

 

  1. Lowe M, Ehlers MM, Ismail F, Peirano G, Becker P, Pitout JDD, Kock MM (2018) Acinetobacter baumannii: epidemiological and antimicrobial susceptibility data from two tertiary academic hospitals in Tshwane, South Africa. Frontiers in Microbiology  9:1280 (doi: 10.3389/fmicb.2018.01280) (IF: 4.165)

 

  1. Laurens JB, Sewell FJJ, Kock MM (2018) Pre-analytical factors related to the stability of ethanol concentration during storage of ante-mortem blood alcohol specimens. Journal of Forensic and Legal Medicine 58:155–163 (IF=1.103)

 

  1. Goolam Mahomed T, Kock MM, Masekela R, Hoosien E, Ehlers MM (2018) Genetic relatedness of Staphylococcus aureus isolates obtained from cystic fibrosis patients at a tertiary academic hospital in Pretoria, South Africa. Scientific Reports 8:12222 (DOI:10.1038/s41598-018-30725-x) (IF=4.122)

 

  1. Hoffman CM, Fritz L, Radebe O, Dubbink JH, McIntyre JA, Kock MM, Peters RPH (2018) Rectal Trichomonas vaginalis infection in South African men who have sex with men. International Journal of STD & AIDS Epub ahead of print DOI: 10.1177/0956462418788418 (IF=1.494)

 

  1. Hoffman CM, Mbambazela N, Sithole P, Morré SA, Dubbink JH, Railton J, McIntyre JA, Kock MM, Peters RPH (2018) Provision of STI services in a mobile clinic reveals high unmet need in remote areas of South Africa: a cross-sectional study. Sexually Transmitted Diseases Oct 22. doi: 10.1097/OLQ.0000000000000931 (IF=1.981)

 

  1. Redelinghuys MJ, Ehlers MM, Bezuidenhoudt JE, Becker PJ, Kock MM (2017) Molecular quantification of Atopobium vaginae and Gardnerella vaginalis in pregnant women. Sexually Transmitted Infections 93(6): 410-415 (IF: 3.015).

 

  1. Schmidt T, Kock MM, Ehlers MM (2017) Molecular characterization of Staphylococcus aureus isolated from bovine mastitis and close human contacts in South African dairy herds: genetic diversity and inter-species host transmission. Frontiers in Microbiology 8:511. doi: 10.3389/fmicb.2017.00511 (IF=4.165).

 

  1. Peters RP, Doyle R, Redelinghuys S, McIntyre JA, Verjans GM, Breuer J, Kock MM (2017) Genital Chlamydia trachomatis biovar L2 infection in South African women. Emerging Infectious Diseases 23(11):1913-1915 (IF: 8.22).

 

  1. Senamela T, Kock M, Becker P, Potgieter JC (2017) Detection of the Janus kinase 2 V617F mutation using a locked nucleic acid real-time PCR assay. Accepted in African Laboratory Journal of Medicine.

 

  1. Peters R, de Vos L, Maduna L, Mudau M, Klausner J, Kock M, Medina-Marino A (2017) Laboratory validation of Xpert® CT/NG and TV testing as performed by nurses at three primary healthcare facilities in South Africa. Accepted in Journal of Clinical Microbiology (IF=3.712)

 

  1. Price CM, Peters RPH, Steyn J, Mudau M, Olivier D, De Vos L, Morikawa E, Kock MM, Medina-Marino A, Klausner JD (2017) Prevalence and detection of Trichomonas vaginalis in human immunodeficiency virus-infected pregnant women. Accepted in Sexually Transmitted Diseases (IF=2.968)

 

Review articles in ISI accredited journals:

  1. Redelinghuys MJ, Ehlers MM, Dreyer AW, Kock MM (2015) Normal flora and bacterial vaginosis in pregnancy: An overview.  Critical Reviews in Microbiology Early Online: 1–12 DOI: 10.3109/1040841X.2014.954522  (IF=6.087).

 

  1. Redelinghuys MJ, Ehlers MM, Dreyer AW, Kock MM (2016) Normal flora and bacterial vaginosis in pregnancy: An overview. Critical Reviews in Microbiology 42:352-363 (IF:8.192)

 

  1. Jung HS, Ehlers MM, Lombaard H, Redelinghuys MJ, Kock MM (2017) Etiology of bacterial vaginosis and polymicrobial biofilm formation. Critical Reviews in Microbiology 43(6):651-667 (IF=6.2)

 

  1. Geldenhuys J, Rossouw TM, Lombaard HA, Ehlers MM, Kock MM (2018) Pre-eclampsia, a pregnancy disorder associated with disruption in the regulation of immune responses. Frontiers in Immunology 9:1659 (IF=5.55)

 

Publications in non-ISI accredited journals:

Book chapters:

  1. Lowings M, Ehlers MM and Kock MM (2015) “Acinetobacter baumannii: A Superbug" has been accepted for publication in the fifth number of the Microbiology Book Series titled "The Battle Against Microbial Pathogens: Basic Science, Technological Advances and Educational Programs"

 

  1. Goolam Mohamed T, Kock MM and Ehlers MM (2015) “Gram-negative bacteria in cystic fibrosis" has been accepted for publication in the fifth number of the Microbiology Book Series titled "The Battle Against Microbial Pathogens: Basic Science, Technological Advances and Educational Programs"

 

  1. De Jesus M, Ehlers M, Dos Santos R, Kock M (2015) Mini-Review: Understanding β-lactamase producing Klebsiella pneumoniae accepted for publication in Antibiotic-Resistant Bacteria. InTech, Croatia, ISBN 978-953-51-4385-7.

 

  1. Schmidt T, Kock MM and Ehlers MM (2015) Antimicrobial resistance in staphylococci at the human-animal interface accepted for publication in Antibiotic-Resistant Bacteria. InTech, Croatia, ISBN 978-953-51-4385-7.

 

 

Conference proceedings (last 5 years):

National:

  1. Goolam Mahomed T, Kock MM, Masekela R, Hoosien E, Ehlers MM (2014) Prevalence and molecular characteristics of dominant bacteria isolated from patients attending a cystic fibrosis clinic in Pretoria. Airwaves congress, from 20 to 23 June 2014 at the Gateway Hotel, Umhlanga (Oral Presentation)

 

  1. Dos Santos RF, Ehlers MM, De Jesus MB, Kock MM (2014) Genetic detection of beta-lactamase genes in Klebsiella pneumoniae and Escherichia coli isolates from wastewater. International Congress on Infectious Diseases, 2-5 April, Cape Town International Convention Centre (Poster presentation)

 

  1. Goolam Mahomed T, Kock MM, Masekela R, Hoosien E, Ehlers MM (2014) Prevalence and molecular characteristics of dominant bacteria isolated from patients attending a cystic fibrosis clinic in Pretoria. Airwaves congress, from 20 to 23 June 2014 at the Gateway Hotel, Umhlanga (Oral Presentation)

 

  1. Strasheim W, Kock MM, Ueckermann V, Hoosien E, Dreyer AW, Ehlers MM (2014) Catheter culture practices in the diagnosis of catheter-related bloodstream infections at a tertiary academic hospital in South Africa. UNIPATH 2014 conference 19-21 September at CSIR ICC, Pretoria, South Africa (Oral presentation)

 

  1. Adelowotan AO, Kock MM, Ehlers MM (2014) Prevalence and characteristics of methicillin-resistant Staphylococcus aureus isolates from a tertiary non-academic hospital in western Nigeria. UNIPATH 2014 conference 19-21 September at CSIR ICC, Pretoria, South Africa (Oral presentation)

 

  1. Adelowotan AO, Kock MM, Olorunju SAS, Ehlers MM (2014) Methicillin-resistant knowledge and level of awareness among patients and healthcare workers at a tertiary hospital in Nigeria. UNIPATH 2014 conference 19-21 September at CSIR ICC, Pretoria, South Africa (Poster presentation)

 

  1. Biswas RK, Ehlers MM, Kock MM (2014) Identification of metronidazole resistance pathway proteins in Trichomonas vaginalis. UNIPATH 2014 conference 19-21 September at CSIR ICC, Pretoria, South Africa (Oral presentation)

 

  1. Biswas RK. Kock M, Ehlers MM (2014) Comparative genomic analysis of methicillin-resistant Staphylococcus aureus. SAGS/SASBi joint conference 2014, Kwalata Raunch, South Africa, 24-26 September 2014 (Poster presentation)

 

Faculty Day 19 & 20 August 2014, Faculty of Health Sciences, School of Medicine, University of Pretoria

  1. Lowings M, Ehlers MM, Louw JE, Ismail F, Lekalakala R and Kock MM (2014) Prevalence of antimicrobial resistance genes and the genetic relatedness of clinical Acinetobacter baumannii isolates circulating in the Pretoria region. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral Presentation) First prize winner in Oral presentation in Clinical Sciences, Junior Researcher

 

  1. Jung HS, Ehlers MM, Hoosien E, Becker PJ, Lekalakala MR and Kock MM (2014)  Presence of multiple vancomycin resistance genes in vancomycin-resistant enterococci. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral Presentation)  Third prize winner in Oral presentation in Clinical Sciences, Junior Researcher

 

  1. Schmidt T, Kock MM, Olorunju SAS and Ehlers MM (2014) Characterisation of staphylococci recovered from bovine intramammary infections and close human contacts in the dairy environment. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral Presentation)  Second prize winner in Oral presentation in Basic Sciences, Junior Researcher

 

  1. Hamiwe T; Kock MM; Lekalakala MR; Ismail F and Ehlers MM (2014) Characterisation of virulence factors of clinical Methicillin-resistant Staphylococcus aureus isolates in Pretoria. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Poster presentation and oral presentation)

 

  1. Humby SA, Ehlers MM, Lekalakala MR, Ismail F and Kock MM (2014) Antimicrobial Resistance Profiles Of Escherichia coli Isolates Collected From a Tertiary Hospital. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Poster presentation)

 

  1. Mhlafu NT, Kock MM, Lekalakala MR, Ismail F, Olorunju SAS and Ehlers MM (2014) Virulence factors associated with clinical Methicillin-susceptible Staphylococcus aureus isolates collected from the Pretoria region. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Poster presentation)

 

  1. Potgieter M, Kock MM, Lekalakala MR, Ismail F and Ehlers MM (2014) Antibiotic susceptibility profiles and molecular identification of methicillin-susceptible Staphylococcus aureus strains circulating in the Pretoria region. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Poster presentation)

 

  1. Schwim RA, Kock MM, Lekalakala MR, Ismail F and Ehlers MM (2014) Antimicrobial resistance of methicillin-resistant Staphylococcus aureus isolates circulating in the Pretoria region. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Poster presentation)

 

  1. Adelowotan AO, Kock MM, Olorunju SAS and Ehlers MM (2014)  Staphylococcal nasal colonisation and associated risk factors among patients and healthcare workers at a tertiary hospital in Nigeria. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Biswas RK, Ehlers MM and Kock MM (2014) Identification of virulence factors and their association in metronidazole resistance from Trichomonas vaginalis. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Dos Santos RF, Ehlers MM, De Jesus MB and Kock MM (2014) Molecular detection of β-lactamase genes in wastewater Klebsiella pneumoniae and Escherichia coli isolates.  Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Goolam Mahomed T, Kock MM, Masekela R, Hoosien E and Ehlers MM (2014) Molecular characterisation and genetic relatedness of Staphylococcus aureus isolates obtained from cystic fibrosis patients. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Louw JE, Ehlers MM and Kock MM (2014) Characterization of resistance genes in Acinetobacter baumannii isolates obtained from wastewater treatment plants.  Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Schoonraad NJ, Kock MM, Van der Zel GA and Ehlers MM (2014) Characterisation of zoonotic Staphylococcus aureus bacteria in slaughtered pigs and abattoir workers in Gauteng, South Africa. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Schoonraad NJ, Kock MM, Van der Zel GA and Ehlers MM (2014) Characterisation of zoonotic Enterococcus faecalis and Enterococcus faecium bacteria in slaughtered pigs and abattoir workers in Gauteng, South Africa. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

  1. Strasheim W, Kock MM, Hoosien M, Ueckermann V, Dreyer AW and Ehlers MM (2014) Surveillance of catheter-related bloodstream infections: The supplemental role of the microbiology laboratory in the detection thereof. Faculty day, Faculty of Health Sciences, 19-20 August 2014 (Oral presentation)

 

Faculty Day 18-19 August 2015, Faculty of Health Sciences, School of Medicine, University of Pretoria

  1. Koekemoer C, Kock MM, Antiabong JF and Ehlers MM (2015) Prevalence of antibiotic-resistant genes in clinical Methicillin-resistant Staphylococcus aureus isolates obtained from a Tertiary Academic Hospital in Pretoria. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Poster

 

  1. Naidoo R, Kock MM, Antiabong JF and Ehlers MM (2015) Identification of virulence genes in clinical methicillin-resistant Staphylococcus aureus isolates obtained from a tertiary academic hospital in Pretoria. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Poster and Poster presentation.

 

  1. Goolam Mohamed T, Kock MM and Ehlers MM (2015) Genetic relatedness of Staphylococcus aureus isolates obtained from patients attending a cystic fibrosis clinic in Pretoria. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Oral presentation

 

  1. Steyn J, Kock MM, Antiabong JF and Ehlers MM (2015) Detection and identification of clinically relevant Enterococcus and Staphylococcus species isolated from surface water in Gauteng. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Poster

 

  1. Pruis N, Ehlers MM, Redelinghuys MJ, Lombaard H, Nene Z and Kock MM (2015) Bacterial vaginosis in pregnant and infertile women. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Poster

 

  1. Osizigbo BI, Ehlers MM and Kock MM (2015) Aetiological pathogens of vaginal discharge and male urethritis syndromes in the Tshwane region. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Oral presentation

 

  1. Majola MS, Ehlers MM, Redlinghuys MJ, Lombard H, Becker PJ and Kock MM (2015) Comparison of rapid tests to gold standard methods for the detection of bacterial vaginosis and Trichomonas vaginalis. Faculty of Health Sciences, Faculty Day, HW Snyman North; 18-19 August 2015. Poster

 

 

International:

  1. De Jesus MB, Ehlers MM, Dreyer AW, Olorunju S, Dos Santos RF, Kock MM (2014) Characterisation of extended-spectrum beta-lactamase-encoding Klebsiella pneumoniae isolates from Pretoria, South Africa. American Society for Microbiology (ASM) 114th General Meeting, 17 – 20 May, Boston, Massachusetts, USA (Poster presentation)

 

  1. Dos Santos RF, Ehlers MM, De Jesus MB, Kock MM (2014) Detection of β-lactamase genes in wastewater Klebsiella pneumoniae and Escherichia coli isolates. American Society for Microbiology (ASM) 114th General Meeting, 17 – 20 May, Boston, Massachusetts, USA (Poster presentation)

 

  1. Ehlers MM, Goolam Mahomed T, Masekela R, Hoosien E, Kock MM (2014) Detection of mecA and Panton-Valentine Leukocidin Toxin genes in Staphylococci isolated from Cystic Fibrosis Patients Attending a Clinic at a Tertiary Academic Hospital in South Africa. American Society for Microbiology (ASM) 114th General Meeting, 17 – 20 May, Boston, Massachusetts, USA (Poster presentation)

 

  1. Strasheim W, Kock MM, Hoosien E, V Ueckermann, Dreyer AW, Ehlers MM (2014) Pathogen distribution of catheter-related bloodstream infections obtained from a tertiary academic hospital in South Africa. American Society for Microbiology (ASM) 114th General Meeting, 17 – 20 May, Boston, Massachusetts, USA (Poster presentation)

 

  1. Adelowotan AO, Kock MM, Ehlers MM (2014) Identification and characterisation of Staphylococcus aureus isolated from nasal swabs obtained from patients and healthcare workers at a tertiary hospital in Nigeria. The 2nd International Congress on Bacteriology and Infectious Diseases, 17 to 19 November 2014, Chicago USA. Poster presentation.

 

  1. Adelowotan AO, Kock MM, Ehlers MM (2014) Characterisation and antibiotic resistance of Staphylococcus aureus isolated from nasal swabs from patients and healthcare workers at a tertiary non-academic hospital in Nigeria.  IMED conference 2014, Vienna, Austria, 31 Oct-3 Nov 2014 (Poster presentation)

 

  1. Adelowotan AO, Kock MM, Antiabong JF and Ehlers MM (2015) Genetic diversity among circulating Staphylococcus aureus strains in a western Nigerian hospital. World Congress on Infectious Diseases, London, UK, 10 to12 August.  Poster.

 

  1. Lowings M, Ehlers MM, Ismail F, Lekalakala MR and Kock MM (2015) Cross-sectional study to determine the circulating antimicrobial resistance genes isolated from Acinetobacter baumannii in two tertiary academic hospitals. Poster and E-poster at the 25th ECCMID conference, 25 – 28 April 2015, Copenhagen, Denmark

 

  1. Strasheim W, MM Kock, E Hoosien, V Ueckermann, AW Dreyer and MM Ehlers (2015) Molecular Epidemiology of Staphylococcus epidermidis at a Tertiary Academic Hospital in Pretoria, South Africa: A Cross-sectional Study.  Oral presentation and E-poster at the 25th ECCMID conference, 25 – 28 April 2015, Copenhagen, Denmark

 

  1. Potgieter M, Kock MM, Lekalakala MR; Ismail F and Ehlers MM (2015) A Cross-sectional Study Determining the Genetic Characteristics of Methicillin-Susceptible Staphylococcus aureus Strains Isolated from Patients in the Pretoria region, South Africa. E-poster at the 25th ECCMID conference, 25 – 28 April 2015, Copenhagen, Denmark

Published abstracts

  1. Dos Santos RF, De Jesus MB, Ehlers MM, Kock MM (2014) Genetic detection of β-lactamase genes in Klebsiella pneumoniae and Escherichia coli isolates from wastewater.  International Journal of Infectious Diseases 21:89

 

Other:

NRF rated members of the group:

Prof MM Ehlers: C2 rated: 

Awards/distinctions of the past 5 years:

Redelinghuys MJ, Ehlers MM, Dreyer AW, Lombaard HA, Kock MM (2013) Comparison of the new Mycofast Revolution assay with a molecular assay for the detection of genital mycoplasmas from clinical specimens.  BMC Infectious Diseases 13:453 (IF=3.12) (1st Runner-up Best Publication Young Researcher Non-clinical 2014)

 

updated 22/05/2019

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