Our research

We work at the interface between parasite biology and drug discovery and use the new biological insights we gain from studying different life cycle forms of the malaria parasite as a catalyst for drug discovery.

We investigate gene regulatory mechanisms underlying the pathogenic processes that drive both asexual proliferation as well as gametocyte differentiation of malaria parasites.  Continue reading…

We focus on the discovery of compounds with transmission-blocking activity, i.e. compounds able to either kill gametocytes or gametes and thereby prevent transmission to mosquitoes. Continue reading…

We translate our findings to the host-parasite interface to understand how transmission-blocking strategies can influence malaria epidemiology, particularly in pre-elimination settings in Africa. Continue reading


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