Current PACRI Projects

  1. Mutational burden and splicing genomics analysis in endocrine positive breast cancer patients who progress after neoadjuvant aromatase inhibitor
  2. Splicing genomic events analysis and targeting for HIV and HPV-associated cervical cancers
  3. Molecular analysis and aberrant splicing events in HPV16 (E6/E7)-associated head and neck oropharyngeal squamous cell carcinomas (HNSCCs) in South Africa
  4. Analysis of long non-coding RNAs (LncRNAs) and alternative splicing modulations in HIV-associated colorectal cancer of black patients
  5. Genome analysis of patients with HIV and HPV-associated oesophageal squamous cell carcinoma (OSCC)
  6. Molecular profiling of colorectal cancer in South African patients and its correlation with HIV infection
  7. Genome analysis of melanoma in South African patients
  8. Molecular profiling of endometrial cancers occurring in Black South African women
  9. Assessing prognostic factors for survival outcomes and late presentation among cancer patients in a hospital setting in South Africa
  10. Linking prostate cancer progression to perineural invasion and neoneurogenesis
  11. Biomarkers of radiotherapy resistance in cervical cancer
  12. Targeting HIV-associated cancers with splicing disruptor drugs
  13. Genome analysis of potential biomarkers for head and neck squamous cell carcinomas (HNSCCs) in a South African Cohort
  14. Profiling long non-coding RNAs (LncRNAs) in prostate cancer

 

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