|12240022||Faculty of Engineering, Built Environment and Information Technology|
|Minimum duration of study: 1 year||Total credits: 128|
The curriculum is determined in consultation with the relevant heads of departments. A student is required to pass modules to the value of at least 128 credits.
The degree is awarded on the basis of examinations only.
Subject to the stipulations of Reg. G.1.3 and G.54, a BEng degree or equivalent qualification is required for admission.
A limited number of appropriate modules from other departments and from other divisions of Chemical Engineering are allowed.
Not all modules listed are presented each year. Please consult the departmental postgraduate brochure.
A student passes with distinction if he or she obtains a weighted average of at least 75% in the first 128 credits for which he or she has registered (excluding modules which were discontinued timeously). The degree is not awarded with distinction if a student fails any one module (excluding modules which were discontinued timeously).
Minimum credits: 128
Description of industrial biotechnology in a process engineering environment. Focus on specific applications in the mining, agricultural, paper and pulp, medical, pharmaceutical, veterinary, brewing and food industries. Principles including implications of bio-prospecting, bio-safety, inoculum production, aseptic growth, quality control and product formulation as applicable to bio-processes. Fermentation with various microbial groups, bio-leaching, gene transfer, solid-substrate fermentation, enzymatic catalysis and immunology. Bioreactors, batch and continuous processing. Bio-remediation.
Introduction to nanotechnology, industrial production of nanomaterials, physico-chemical properties of nanomaterials, identification of nanomaterials sources (point vs diffuse sources) to aquatic systems. Fate, behaviour and transport of nanomaterials in different environmental media (freshwater, sediments, wastewater, and soil). Fractal theory and transformation pathways of nanomaterials: chemical, biological, physical and interactions with macromolecules transformations. Nanoecotoxicology: concept of toxicity within nanomaterials regime, nanomaterials toxicity tests (acute vs. chronic toxicity), mechanisms of nanomaterials toxicity, biocompatibility of nanomaterials, bioaccumulation and persistence. Risk assessment paradigm: Hazard identification (production volumes, material flows, nanowastes generation, bioaccumulation, long-range transport, and persistence), hazard characterization (in vitro vs. in vivo studies, adverse outcome pathways), exposure assessment (life cycle assessment and environmental uptake), risk assessment, and risk management (regulation, nanowastes and by-products management protocols). Sustainable nanotechnology paradigm: safe-by-design concept, risk modelling and predictions.
In depth understanding of the important metabolic pathways in microorganisms, black box models for describing stoichiometry of bioreactions, metabolic flux analysis as the basis for metabolic (genetic) engineering, kinetics of microbial conversions and basic bioreactor design.
Design, construction and testing of experimental setup. Initial test experiments, calibrations and modifications. Preliminary results. Experimental plan and schedule for the research dissertation. Detailed predictions on anticipated measurements. Directly relevant literature (core essentials taken from CIR 702).
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