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Prof. Namrita (N) Lall

NRF/DST Chair: Plant health Products from IKS
Professor Plant Science
Section: Medicinal Plant Science
 
Office: Plant Sciences Complex 3-39
Tel:  +27 (0)12 420 2524
Fax: +27 (0)12 420 6668
Email: namrita.lall[AT]up.ac.za
 

 

My main interest include bioprospecting of medicinal plants. In particular research involves with exploring the antituberculosis natural product leads from medicinal plants, susceptibility studies of other bacteria to medicinal plants, cytotoxicity of plant extracts/compounds, anticancer activity, antityrosinase (skin pigmentation), anti-acne activity of medicinal plants, isolation and purification of bioactive principles from plants. Scientific exploration integrates the basic and applied Sciences.  Research is being conducted in collaboration with scientistis from other fields and aim is to obtain valuable pharmaceutical and cosmeceutical products from medicinal plants. 

 

Selected publications:

  • Lall N, Kumar V, Meyer D, Gasa N, Hamilton CJ, Matsabisa M, Oosthuizen CB. (2016). In vitro and In vivo antimycobacterial, hepatoprotective and immunomodulatory activity of Euclea natalensis and its mode of action. Journal of ethnopharmacology 194, 740-748

  • Lall N, Kishore N, Momtaz S, Hussein A, Naidoo S, Nqephe M, Crampton B. (2015) Extract from Ceratonia siliqua exhibits depigmentation properties. Phytotherapy research 29 (11), 1729-1736

  • Sharma R, Lall N. (2014) Antibacterial, antioxidant activities and cytotoxicity of plants against Propionibacterium acnes. South African Journal of Science 110 (11-12), 01-08

  • Lall N, Kishore N. (2014) Are plants used for skin care in South Africa fully explored? Journal of ethnopharmacology 153 (1), 11 61-84

  • Karkare S, Chung TTH, Collin F, Mitchenall LA, McKay AR, Greive SJ, Meyer JJM, Lall N, Maxwell A. (2013). The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action. Journal of Biological Chemistry 288 (7), 5149-5156

  • Lall N, Henley-Smith CJ, De Canha MN, Oosthuizen CB, Berrington D. (2013) Viability reagent, prestoblue, in comparison with other available reagents, utilized in cytotoxicity and antimicrobial assays. International journal of microbiology 2013

  • Berrington D, Lall N. (2012) Anticancer activity of certain herbs and spices on the cervical epithelial carcinoma (HeLa) cell line. Evidence-Based Complementary and Alternative Medicine 2012

  • Mativandlela SPN, Meyer JMM, Hussein AA, Houghton PJ, Hamilton CJ, Lall N. (2008). Activity against Mycobacterium smegmatis and M. tuberculosis by extract of South African medicinal plants. Phytotherapy Research 22 (6), 841-845

  • Lall N, Meyer JJM. (1999). In vitro inhibition of drug-resistant and drug-sensitive strains of Mycobacterium tuberculosis by ethnobotanically selected South African plants. Journal of ethnopharmacology 66 (3), 347-354

 

I have been placed in the Essential Science Indicators list of the top 1% of publication outputs (citations) in the discipline PHARMACOLOGY and TOXICOLOGY. I have made a significant contribution to the field of Medicinal Plant science. Several medicinal plants with valuable biological activities have been discovered which led to several patents. I have obtained several international patents including 3 US patents, 4 PCT-patents, 8 South African patents, co-authored about 130 research articles in peer reviewed journals and ten book chapters. A book on medicinal plants has recently been published by Elsevier edited by myself.

 

Students and Post-doc:

Post-doc:

Dr. Surjeet Verma

Dr. Danielle Twilley

Dr. Carel Oosthuizen

PhD:

Blom-Van-Staden, A

Bodiba, D

De Canha, MN

Henley-Smith, CJ

Lambrechts, I

Reid, A

Sharma, R

 

MSc:

Fibrich, BD

Gasa, N

Labuschagne, T

Le Roux, K

Nqephe, M

Rademan, S

Szuman, K

 

 

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