Name: Prof R Anderson

e-mail: [email protected]

Tel: 012 319 2425

 

Publications of the past 5 years:

Original publications in ISI accredited journals:

1. Feldman C, Normark S, Henriques-Normark B, Anderson R. Pathogenesis and prevention of cardiovascular events in patients with pneumococcal community-acquired pneumonia. Journal of Internal Medicine (provisionally accepted with minor changes; manuscript no.: JIM-18-0795;  IF:7.98).

 

2. Steel HC, Venter WDF, Theron AJ, Anderson R, Feldman C, Kwofie L, Cronje T, Arullapan N, Rossouw T. Effects of tobacco usage and antiretroviral therapy on biomarkers of systemic immune activation in HIV-infected participants. Mediators of Inflammation (in press; manuscript no.: 8357109; IF:3.549).

 

3. Anderson R, Theron AJ, Nel JG, Durandt C, Cholo MC, Feldman C, Tintinger GR. Clofazimine, but not isoniazid or rifampicin, augments platelet activation in vitro. Frontiers in Pharmacology – Inflammation Pharmacology 2018; 9: (doi: 10.3389/fpharm.2018.01335; IF: 3.831)

 

4. Richards GA, Theron AJ, Tintinger GR, Anderson R. The effects of dabigatran and rivaroxaban on markers of polymorphonuclear leukocyte activation. Pharmaceuticals 2018; 11(2): E46; doi: 10.3390/ph11020046.  (Scopus accredited; RG IF: 5.3; PubMed indexed; ISI IF pending).

 

5. Anderson R, Nel JG, Feldman C. Review: Multifaceted role of pneumolysin in the pathogenesis of myocardial injury in community-acquired pneumonia. International Journal of Molecular Science 2018; 19(4): 1147; doi: 10.3390/ijms19041147. (IF 3.687).

 

6. Anderson R, Rapoport BL. Immune dysregulation in cancer patients undergoing immune checkpoint inhibitor treatment and potential applications for future clinical practice.  Frontiers in Oncology 2018; 8: 80; doi: 10.3389/fonc.2018.00080. (ISI indexed; IF: 4.4).

 

7. Feldman C, Anderson R. Pneumonia as a systemic illness. Current Opinion in Pulmonary Medicine 2018; 24(3): 237–243; doi: 1097/MCP.0000000000000466. (IF: 2.884).

 

8. Rossouw TM, Theron AJ, Anderson R. Practical approach to diagnosis and management of primary immunodeficiency diseases. South African Family Practice 2018; 60(5): 42–49 (IF:0).

 

9. Meyer PWA, Ally MTM, Hodkinson B, Anderson R, Tikly M. Diagnostic utility of, and influence of tobacco usage and genetic predisposition on, immunoglobulin A rheumatoid factor and anti-citrullinated peptide autoantibodies in South African rheumatoid arthritis patients. African Health Sciences 2018; 18(2): 295–303 (IF 0.67).

 

10. Meyer PWA, Ally MTM, Hodkinson B, Anderson R, Tikly M. Comparison of the diagnostic potential of three anti-citrullinated protein antibodies as adjuncts to rheumatoid factor and CCP in a cohort of South African rheumatoid arthritis patients. Rheumatology International 2018; 38(6): 993–1001; doi: 10.1007/s00296-018-4036-y. (IF 1.952)

 

11. Meyer PW, Anderson R, Ker JA, Ally MT. Rheumatoid arthritis and risk of cardiovascular disease. Cardiovascular Journal of Africa 2018; 29(5): 317–321 doi: 10.5830/CVJA-2018-018. (IF 1.022).

 

12. Anderson R, Feldman C. Pneumolysin as a potential therapeutic target in severe pneumococcal disease. Journal of Infection 2017; 74(6): 527–544. doi: 10.1016/j.jinf.2017.03.005 (IF: 4.441 )

 

13. Feldman C, Anderson R. Cardiac troponin T as a predictor of short- and long-term mortality in community-acquired pneumonia. Respirology 2017; 22(5): 845–846.  doi: 10.1111/resp.13020 [Editorial] (IF: 3.257)

 

14. Bokaba RP, Anderson R, Theron AJ, Tintinger GR. Cigarette smoke condensate attenuates phorbol ester-mediated neutrophil extracellular trap formation. African Health Sciences 2017; 17(3):896–904. Doi: 10.4314/ahs.v17i3.33 (IF: 0.635)

 

15. Opolot JO, Theron AJ, MacPhail P, Feldman C, Anderson R. Effect of smoking on acute phase reactants, stress hormone responses and vitamin C in pulmonary tuberculosis. African Health Sciences 2017; 17(2):337-345. Doi:10.4314/ahd.v17i2.7 (IF: 0.635)

 

16. Nel JG, Durandt C, Theron AJ, Tintinger GR, Pool R, Richards GA, Mitchell TJ, Feldman C, Anderson R. Pneumolysin mediates heterotypic aggregation of neutrophils and platelets in vitro. Journal of Infection 2017; 74(6): 599–608. doi: 10.1016/j.jinf.2017.02.010 (IF: 4.441)

 

17. Anderson R, Feldman C. Review: Mechanisms of platelet activation by the pneumococcus and the role of platelets in community-acquired pneumonia (Review). Journal of Infection 2017; doi: 10.1016/j.jinf.2017.09.013 [Epub ahead of Print]. (IF: 4.441)

 

18. Theron AJ, Anderson R, Rossouw TM, Steel HC. Review: The role of transforming growth factor beta-1 in the progression of HIV/AIDS and development of non-AIDS-defining fibrotic disorders (Review). Frontiers in Immunology, 2017; 8:1461. doi: 10.3389/fimmu.2017.01461 (IF: 6.42)
19. Feldman C, Anderson R. Editorial: Fatty acid-binding proteins as biomarkers of disease severity and outcome in community-acquired pneumonia. Annals of Translational Medicine 2016; 4(19) : 380 (4 pages; doi: 10.21037/atm.2016.08.50)
20. Feldman C, Anderson R, Rossouw TM. Invited Review: HIV-related pneumococcal disease prevention in adults. Expert Review in Respiratory 2017; 11(3):599-608. Doi:10.1016/j.jinf.2017.02.010. (Invited review) (IF:2.278).

 

21. Cholo M, Mothiba M, Fourie B, Anderson R. Review: Mechanisms of action and therapeutic efficacies of the lipophilic antimycobacterial agents clofazimine and bedaquiline. Journal of Antimicrobial Therapy 2017; 72(2):338-353  doi: 10.1093/jac/dkw426. (IF:5.313)

 

22. Feldman C, Anderson R. Review: The role of Streptococcus pneumoniae in community-acquired pneumonia. Seminars in Respiratory and Critical Care Medicine 2016; 37(6): 1-13. (IF: 2.712)

 

23. Feldman C, Anderson R. Review: Epidemiology, virulence factors and management of the pneumococcus. F1000Research 2016; 5: 3230. (11 pages, Pub Med listed, IF N/A)

 

24. Feldman C, Anderson R. Review: Community-acquired pneumonia: still a major burden of disease. Current Opinion in Critical Care 2016; 22(5): 477-484 (IF: 3.183).

 

25. Govind N, Ally MM, Tikly M, Anderson R, Hodkinson B, Meyer PW. Pitfalls in the assessment of smoking status detected in a cohort of South African RA patients. Rheumatology International 2016; 36(10): 1365-1369. (IF: 1.702)

 

26. Feldman C, Anderson R. Review: Prevalence, pathogenesis, therapy and prevention of cardiovascular events in patients with community-acquired pneumonia. Pneumonia 2016; 8: 11 (10 pages, PubMed indexing and IF pending)

 

27. Ally MMTM, Meyer PWA, Anderson R. Review: Early rheumatoid arthritis: focus on RA in the developing world. South African Journal of Family Practice 2016; 1(1): 1–3. [Early on line]. Doi: 10.1080/20786190.2016.1177988. (IF: 0)

 

28. Anderson R,  Meyer PWA, Ally MTM, Tikly M. Review: Smoking and air pollution as pro-inflammatory triggers for the development of rheumatoid arthritis. Nicotine and Tobacco Research 2016; 18(7)): 1556-1565 (IF: 3.296)

 

29. Nel JG, Durandt C, Mitchell TJ, Feldman C, Anderson R, Tintinger GR. Review: Pneumolysin mediates platelet activation in vitro. Lung 2016; 194(4): 589-593 (IF: 2.171)

 

30. Nyale GM, Anderson R, Patel AR, Feldman C. A 10 years audit of cardiothoracic referrals from a pulmonology service in a developing country: impact of patient human immunodeficiency virus status. Annals of Translational Medicine 2016; 4(7):132. Doi: 10.21037/atm.2016.03.56. (PubMed indexed, IF pending)

 

31. Makhubele TG, Steel HC, Anderson R, van Dyk G, Theron AJ, Rossouw TM. Review: Systemic immune activation profiles of HIV-1 subtype C-infected children and their mothers Mediators of Inflammation 2016; 2016:9026573. (IF: 3.418)

 

32. Feldman C, Anderson R. Review: Corticosteroids in the adjunctive therapy of community-acquired pneumonia: an appraisal of recent meta-analyses of clinical trials. Journal of Thoracic Disease 2016; 8(3): E162–E171 (IF: 1.783)

 

33. Feldman C, Anderson R. Review: Bacterial respiratory infections complicating Human Immunodeficiency Virus. Seminars in Respiratory and Critical Care Medicine 2016; 37(2):214–229. (IF: 2.712)

 

34. Meyer PWA, Ally MTM, Anderson R. Reliable and cost-effective serodiagnosis of rheumatoid arthritis. Rheumatology International 2016; 36(6):751–758 (IF: 1.702)

 

35. Nel JG, Theron AJ, Durandt C, Tintinger GR, Pool R, Mitchell TJ, Feldman C, Anderson R. Review: Pneumolysin activates neutrophil extracellular trap formation. Clinical and Experimental Immunology 2016; 184(3):358–367. (IF: 3.148)

 

36. Nel JG, Theron AJ, Durandt C, Tintinger GR, Pool R, Anderson R. Review: Neutrophil extracellular traps and their role in health and disease. South African Journal of Science 2016; 112; 1-9 (IF: 1.031)

 

37. Cholo MC, van Rensburg EJ, Osman AG, Anderson R. Expression of the genes encoding the Trk and Kdp potassium transport systems of Mycobacterium tuberculosis. Biomedical Research International 2015; 2015:608682. doi: 10.1155/2015/608862, 11 pages (IF: 2.13)

 

38. Feldman C, Anderson R. (Review) Community-acquired pneumonia: Pathogenesis of acute cardiac events and potential adjunctive therapies. Chest 2015; 48: 523-532 (IF:7.483)

 

39. Rossouw TM, Anderson R, Feldman C. (Review) Impact of HIV infection and smoking on lung immunity and related disorders. European Respiratory Journal 2015; 46: 1781-1795  (IF:8.322)

 

40. Tintinger GR, Theron AJ, Steel HC, Feldman C, Anderson R. (Review) Formoterol is more effective than salmeterol in suppressing neutrophil reactivity. European Respiratory Journal Open Research 2015; 1: 00014-2015. Doi 10.1183/23120541.00014-2015 (new journal, now PubMed indexed, IF pending)

 

41. Ally MTM, Hodkinson B, Meyer PW, Musenge E, Tintinger G, Tikly M, Anderson R. Circulating anti-citrullinated peptide antibodies and cytokines as biomarkers of response to disease-modifying antirheumatic drugs therapy in early rheumatoid arthritis. BMC Musculoskeletal Disorders 2015; 16:130. Doi: 10.1186/s12891-015-0587-1 (1.90)

 

42. Mothiba MT, Anderson R, Fourie B, Germishuizen WA, Cholo MC. Effects of clofazimine on planktonic and biofilm growth of Mycobacterium tuberculosis and Mycobacterium smegmatis. Journal of Global Antimicrobial Resistance 2015; 3: 13-18.  (1.087)

 

43. Selvam A, Buhimschi IA, Makin JD, Pattinson RC, Anderson R, Forsyth W. Investigating markers of inflammation and oxidative stress in the cord blood of HIV-exposed, uninfected (HEU) infants. HIV Medicine 2015; 16:375–380. doi: 10.1111/hiv 12214. (3.341)

 

44. Opolot JO, Theron AJ, Anderson R, Feldman C. Acute phase proteins and stress hormone responses in patients with newly diagnosed smear positive tuberculosis. Lung 2015; 193(1): 13-18. (2.00)

 

45. Mokgobu MI, Cholo MC, Anderson R, Steel HC, Motheo MP, Hlatshwayo TN, Tintinger GR, Theron AJ. Oxidative induction of pro-inflammatory cytokine production by human monocyte-derived macrophages following exposure to manganese in vitro. Jounal of Immunotoxicology 2015; 12(1): 98-103. (2.054)

 

46. Masekela R, De Boeck C, Steel HC, Vreys M, Tintinger GR, Anderson R, Green R. Expression of soluble triggering receptor expressed on myeloid cells-1 in childhood CF and non-CF bronchiectasis. Pediatric Pulmonology 2015; 50: 333-339. (2.85)
47. Feldman C, Anderson R. Recent advances in our understanding of Streptococcus pneumoniae infection. F1000 Prime Reports 2014; 6:82 (doi: 10.12703/P6-82, 10 pages).(PubMed indexed, IF N/A)

 

48. Feldman C, Anderson R. Review: Current and new generation pneumococcal vaccines. Journal of Infection 2014; 69(4): 309-325. (4.441)

 

49. Cockeran R, Herbert JA, Mitchell TJ, Dix-Peek T, Dickens C, Anderson R, Feldman C. Exposure of a 23F serotype strain of Streptococcus pneumoniae to cigarette smoke condensate is associated with upregulation of genes encoding the two-component regulatory system 11 (TCS11). Biomedical Research International 2014; 2014: Article ID:976347, 4 pages. (2.13)

 

50. Theron AJ, Steel HC, Tintinger GR, Gravett CM, Anderson R, Feldman C. Cysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell function. Journal of Immunology Research 2014; 2014: Article ID 608930, 16 pages. (2.812)

 

51. Adebayo SA, Shai LJ, Cholo MC, Anderson R, du Toit D. Assessment of the pro-inflammatory activity of water sampled from major water treatment facilities in the greater Pretoria region. Water SA 2014; 40, 379-383. (0.809)

 

52. Malherbe G, Steel HC, Cassol S, de Oliveira T, Seebregts C, Anderson R, Cassol E, Rossouw TM. Circulating biomarkers of immune activation distinguish viral suppression from non-suppression in HAART-treated patients with advanced HIV-1 subtype C infection. Mediators of Inflammation 2014; 2014: Article ID 198413, 7 pages. (3.418)

 

53. Anderson R, Theron AJ, Steel HC, Durandt C, Tintinger GR, Feldman C. The beta-2-adrenoreceptor agonists, formoterol and indacaterol, but not salbutamol, effectively suppress the reactivity of human neutrophils in vitro. Mediators of Inflammation 2014; 2014: Article ID 105420, 9 pages. (3.418)

 

54. Anderson R, Tintinger GR, Feldman C. Inflammation and Cancer: The role of the human neutrophil. South African Journal of Science 2014; 110: 36-41. (1.031)

 

 

Book Chapters:

 

1. Feldman C, Anderson R. Community-acquired pneumonia. In: Textbook of Pulmonary and Critical Care Medicine (2^nd edition). Ed. SK Jindal. Published by Jaypee Brothers Medical Publishers Ltd (scheduled for July 2016).

 

2. Hauser C, Anderson R, Feldman C. Bacterial respiratory and invasive pneumococcal infections and human immunodeficiency virus (HIV) infection. In: Encyclopedia of AIDS. Eds.: Hope T, Richman DD, Stevenson M, Springer Publishing, New York. Doi:10.1007/978-1-4614-9610-6_421-1.

 

3. Feldman C, Anderson R. Respiratory Infections in Specific Populations: HIV patients, Chapter 9. In: Textbook of Respiratory and Critical Care Infections. Blasi F and Dimopoulos G (eds). Jaypee Brothers Medical Publishers, New Delhi, India, 2015; pp. 139-158. (ISBN 978-93-5090-298-1).

 

4. Feldman C, Anderson R. Community Acquired Pneumonia. In: Jindal SK (ed): Handbook of Pulmonary and Critical Care Medicine: A developing countries perspective, Jaypee Brothers, Medical Publishers, New Delhi India, Chapter 20, pp. 148-154, 2012 (Second edition will be published during 2015). (ISBN: 978-93-5025-073-0).

 

5. Feldman C, Anderson R. Bacterial community-acquired pneumonia, Chapter 8 In: ERS Monograph - Pulmonary Complications of HIV. Feldman C, Polverino E & Ramirez JA (eds). European Respiratory Society Publications. 2014; pp. 98-111. (ISBN – electronic – 978-184-98-4055-2.