Name: Prof Michael Pepper

e-mail: [email protected]

Tel: 012 319 2190

Cell: 072 209 6324

 

 

Publications of the past 5 years:

 

 

Original publications in ISI accredited journals:

 

 

1. Anderson R., Theron A.J., Steel H, C., Durandt C., Tintinger G.R., Feldman C. The beta-2-adrenoreceptor agonists, formoterol and indacaterol, but not salbutamol, effectively suppress the reactivity of human neutrophils in vitro. Mediators Inflamm. 6: 105420 (2014)

 

2. Grant C.C., Janse van Rensburg D.C., Pepper M.S., du Toit P.J., Wood P.S., Ker J., Krüger P.E., Grobbelaar C.W., Nolte K., Fletcher L. and Grant T.C.  The correlation between the health-related fitness of healthy participants measured at home opposed to fitness measured by sport scientists in a laboratory. S. Afr. Family Practice. 56: 235-239 (2014).

 

3. Mabeta P. and Pepper M.S. Altered expression of platelet factor 4 and basic fibroblast growth factor correlates with the inhibition of tumor growth in mice. Biomedicine & Pharmacotherapy 69: 186-190 (2015).

 

4. Myburgh R., Ivic S., Pepper M.S., Gers-Huber G., Li D., Audigé A., Rochat M.A, Jaquet V., Regenass S., Manz M.G, Salmon P., Krause K.H. and Speck R.F. Lentivector knock-down of CCR5 in hematopoietic stem cells confers functional and persistent HIV-resistance in humanized mice. J. Virol. 89: 6761-6772 (2015).

 

5. Mellet J., Alessandrini M., Steel H.C and Pepper M.S. Constituting a public umbilical cord blood bank in South Africa. Bone Marrow Transplantation. 50: 615-616 (2015).

 

6. Taylor J., Anyango J.O., Potgieter M., Kallmeyer K., Naidoo V., Pepper M.S and Taylor J.R.N. Biocompatibility and biodegradation of protein microparticle and film scaffolds made from kafirin (sorghum prolamin protein) subcutaneously implanted in rodent models. Journal of Biomedical Materials Research: Part A. 103A: 2582–2590 (2015).

 

7. Dodgen T.M., Eloff A., Mataboge C., Roos J.L., van Staden C.W. and Pepper M.S. Relationship between risperidone-associated adverse drug reactions and CYP2D6 polymorphisms in the South African population: a pilot study. Appl. Translational Genomics. 5: 40-46 (2015).

 

8. Dodgen T.M., Drögemöller B.I., Wright G.E.B, Warnich L., Steffens F.E, Cromarty A.D, Alessandrini M. and Pepper M.S. Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South African cohort. Pharmacogenomics. 16: 1343-1354 (2015).

 

9. Dodgen T.M., Labuschagne C. de J., van Schalkwyk A., Steffens F.E., Gaedigk A., Cromarty A.D., Alessandrini M and Pepper M.S. Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort. Pharmacogenomics J. 17, 393 (2016)

 

10. Mellet J., Gray C.M. and Pepper M.S. Conventional HLA typing techniques vs. next-generation sequencing in a South African cohort.  S. Afr. Med. J. 106: 88-91. (2016).

 

11. Durandt C., van Vollenstee F., Kallmeyer K., de Villiers D., Honing C., Potgieter M. and Pepper M.S. Novel flow cytometric approach for the detection of adipocyte subpopulations during adipogenesis. J Lipid Res. 57: 729–742 (2016).

 

12. Ambele M.A., Dessels C., Durandt C. and Pepper M.S. Genome-wide analysis of gene expression during adipogenesis in human adipose-derived mesenchymal stromal cells reveals novel patterns of gene expression during adipocyte differentiation. Stem Cell Res. 16: 725-734 (2016).

 

13. Dzobo K., Turnley T., Wishart A., Rowe A., Kallmeyer K., van Vollenstee F.A., Thomford N.E., Dandara C., Chopera D., Pepper M.S. Parker M.I. Fibroblast-derived extracellular matrix induces chondrogenic differentiation in human adipose-derived mesenchymal stromal/stem cells in vitro. Int. J. Mol. Sci. 17: 1259 (2016).

 

14. Dodgen T.M., Labuschagne C. de J., van Schalkwyk A., Fickl H., Steffens F.E., Gaedigk A., Cromarty A.D. and Pepper M.S. Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort. Pharmacogenomics J. 16: 566-572 (2016).

 

15. Mahomed S., Slabbert M.N. and Pepper M.S. Social justice and research using human biological material: A right to respond. S. Afr. Med. J. 106: 841 (2016)Dzobo K., Vogelsang M., Dandara C., Kallmeyer K., Pepper M.S., Parker M.I. and Thomford N.E. Wharton’s Jelly-derived mesenchymal stromal cells and fibroblast-derived extracellular matrix synergistically activate apoptosis in a p21-dependent mechanism in WHCO1 and MDA MB 231 cancer cells in vitro. Stem Cells Int. Published online 2016 Jan 10.  doi:  10.1155/2016/4842134 (2016).

 

16. van Vollenstee F.A, Jackson C., Hoffmann D., Potgieter M., Durandt C. and Pepper M.S. Human adipose-derived mesenchymal stromal cells transduced with GFP lentiviral vectors: assessment of immunophenotype and differentiation capacity in vitro. Cytotechnology. 68: 2049-2060  (2016)

 

17. Janse van Rensburg D.C., Grant C.C., Jansen van Rensburg A., Botha R.P.G., Wood P.S., Nolte K., Fletcher L., du Toit P.J., Pepper M.S. and Kruger P.E. The FitTrack Index as fitness indicator: A pilot study. Health SA Gesondheid. 21: 431-436 (2016).

 

18. Mahomed S., Slabbert M.N. and Pepper M.S. Ownership and human tissue - the legal conundrum: A response to Jordaan’s critique. S. Afr. Med. J. 107:196-198 (2017).

 

19. Ambele M.A and Pepper M.S. Identification of transcription factors potentially involved in human adipogenesis in vitro. Mol. Genet. Genomic Med. 5: 210-222 (2017).

 

20. Dodgen T.M., Labuschagne C. de J., van Schalkwyk A., Steffens F.E., Gaedigk A., Cromarty A.D. and Pepper M.S. Pharmacogenetic comparison of CYP2D6 predictive and measured phenotypes in a South African cohort. Pharmacogenomics J. 17: 393 (2017)

 

21. Choudhry M., Alessandrini M., Rademan J., Dodgen T.M., Steffens F.E, van Zyl D.G, Gaedjik A. and Pepper M.S. Impact of CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy: A pilot study. Pharmacogenomics. 18: 433-443 (2017).

 

22. Jackson C.S., Durandt C., Janse van Rensburg I., Praloran V., Brunet de la Grange P. and Pepper M.S Targeting the Aryl hydrocarbon receptor nuclear translocator complex with DMOG and Stemregenin 1 improves primitive hematopoietic stem cell expansion. Stem Cell Res. 21: 124-131 (2017).

 

23. Nel J-G, Durandt C, Theron AJ, Tintinger GR, Pool R, Richards GA, Mitchell TJ, Feldman C. and Anderson R. Pneymolysin mediates heterotypic aggregation of neutrophils and platelets in vitro. J Infect. 74, 599-608 (2017).

 

24. Choudhury A., Ramsay M., Hazelhurst S., Aron S., Bardien S., Botha G., Chimusa E., Christoffels A., Gamieldien J., Sefid Dashti M.J., Joubert F., Meintjes A., Mulder N., Ramesar R., Rees J., Scholtz K.,  Sengupta D., Soodyall H., Venter P., Warnich L. and Pepper M.S. Whole genome sequencing for an enhanced understanding of genetic variation among South Africans. Nature Commun. 8: 2062 (2017).

 

25. Kappala S., Alessandrini M., Matlhako T., Beltchev E., Pool R., and Pepper M.S. Application of the AMLprofiler microarray diagnostic in the South African setting. Stem Cells Int. Volume 2017, Article ID 2560191, 8 pages (2017).

 

26. Naidoo A., Ramsuran V., Chirehwa M., Denti P., McIlleron H., Naidoo K., Yende-Zuma N., Singh R., Ngapu S., Chaudhry M., Pepper M.S. and Padayatchi N. Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African tuberculosis patients. Pharmacogenomics. Pharmacogenomics. 19: 17-29 (2018).

 

27. Dessels C., Durandt C. and Pepper M.S. Comparison of human platelet lysate alternatives using expired and freshly isolated platelet concentrates for adipose-derived stromal cell expansion. Platelets. 19: 1-12 (2018).

 

28. Tshabalala M., Ingram C., Schlaphoff T., Borrill V., Christoffels A., Pepper M.S. Human Leukocyte Antigen-A, B, C, DRB1, and DQB1 Allele and Haplotype Frequencies in a Subset of 237 Donors in the South African Bone Marrow Registry. J. Immunol. Res. 23:2031571 (2018).

 

29. Stander B.A., van Volenstee F., Kallmeyer K., Potgieter M., Swanepoel A., Joubert A., Moolman S., Kotze L., Pepper M.S. An in vitro and in vivo study on the properties of hollow polycaprolactone cell-delivery particles. PLoS One 13(7): e0198248 (2018).

 

30. Ambele M.A., Pepper M.S., van Heerden M.B. and van Heerden W.F.P. Heterozygosity of p16 expression in an oral squamous cell carcinoma with associated loss of heterozygosity and copy number alterations. Head & Neck. Dec 14. doi: 10.1002/hed.25566. [Epub ahead of print] PubMed PMID: 30552721. (2018).

 

 

Publications in non-ISI accredited journals:

 

 

31. Logan M., van der Merwe M.T., Dodgen T., Myburg R., Eloff A., Alessandrini M. and Pepper M.S. Allelic variants of the Melanocortin 4 receptor (MC4R) polymorphisms in a South African study group. Mol. Genet. Genomic Med. 4: 68-76 (2016).

 

32. Meisner-Roloff M., Gaggia L., Vermeulen M., Haeri Mazanderani A., du Plessis N.M., Steel H. and Pepper M.S. Strategies for screening cord blood for a public cord blood bank in high HIV prevalence regions. Global Health, Epidemiol. Genomics. 3: e9 (2018).

 

33. Pepper M.S. Genome technologies, precision medicine and innovative therapies. Quest 14(3): a1 (2018)

 

 

Review articles in ISI accredited journals:

 

1. Alessandrini M. and Pepper M.S.  Priority pharmacogenetics for the African continent:  focus on cytochrome P450. Pharmacogenomics  15: 385-400 (2014)

 

2. Čolić A., Alessandrini M. and Pepper M.S. Pharmacogenetics of CYP2B6, CYP2A6, and UGT2B7 in HIV treatment in African populations: focus on efavirenz and nevirapine. Drug Metabolism Reviews Nov 47:111-123 (2015).

 

3. Kallmeyer K. and Pepper M.S. Homing properties of mesenchymal stromal cells. Expert Opinion on Biological Therapy. 15: 477-479 (2015)

 

4. Atashi F., Modarressi-Ghavami A. and Pepper M.S. The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review. Stem Cells and Development. 24: 1150-1163 (2015)

 

5. van der Westhuizen F.H., Sinxadi P., Dandara C., Smuts I., Riordan G., Meldau S., Malik A., Sweeney M., Tsai Y., Towers W., Louw R., Gorman G., Payne B., Soodyall H., Pepper M.S. and Elson J. Understanding the implications of mitochondrial DNA variation in the health of black southern African populations: the 2014 Workshop. Human mutation. Human mutation. 36: 569-571 (2015)

 

6. Pepper M.S. Gender and sexual diversity. Changing paradigms in an ever-changing world. S. Afr. Med. J. 105: 746-747 (2015).

 

7. Pepper M.S. SAJBL – Flagship special stem cell issue. S. Afr. J. Bioethics Law. 8: 2-3 (2015).

 

8. Pepper M.S., Slabbert M.N. Human tissue legislation in South Africa: focus on stem cell research and therapy. S. Afr. J. Bioethics Law. 8: 4-11 (2015).

 

9. Slabbert M.N. and Pepper M.S. A global comparative overview of the legal regulation of stem cell research and therapy: lessons for South Africa? S. Afr. J. Bioethics Law. 8: 12-22 (2015).

 

10. Slabbert M.N., Pepper M.S. and Mahomed S. Stem cell tourism in South Africa: a legal perspective. S. Afr. J. Bioethics Law. 8: 41-45 (2015).

 

11. Reznichenko A.S., Huyser C. and Pepper M.S. Mitochondrial transfer: ethical, legal and social implications in assisted reproduction. S. Afr. J. Bioethics Law. 8:32-35 (2015).

 

12. Pepper M.S., Gouveia C. and Slabbert M.N. Legislation governing pluripotent stem cells in South Africa. S. Afr. J. Bioethics Law. 8: 32-35 (2015).

 

13. Botes W.M., Alessandrini M. Legal implications of translational promises of unproven stem cell therapy. S. Afr. J. Bioethics Law. 8:36-40 (2015).

 

14. Chira S., Jackson C.S., Oprea I., Ozturk F., Pepper M.S., Diaconu I., Braicu C., Calin G., Berindan-Neagoe I. Progress towards safe and efficient gene therapy vectors. Oncotarget. 6: 30675-30703 (2015).

 

15. Tshabalala M., Mellet J. and Pepper M.S. Human leukocyte antigen (HLA) diversity: a southern African perspective. J. Immunol. Res. Volume 18: Article ID 746151, 11 pages (2015).
16. Stewart C. Pepper M.S. Cystic fibrosis on the African continent. Genet. Med. 18: 653-662 (2016).

 

17. Meldau S., Riordan G., van der Westhuizen F., Elson J.L, Smuts I., Pepper M.S and Soodyall H. Could we offer mitochondrial donation or similar assisted reproductive technology to South African patients with mitochondrial DNA disease?  S. Afr. Med. J. 106: 234-236 (2016).

 

18. Lombard Z., Aldous C., Baine F., Fieggen K., Henderson B., Hoal E., Kinnear C., Kinsley N., Krause A., Lochan A., Macaulay S., September A., Spencer C., Urban M., Soodyall H., Pepper M., Ramsay M. and de Vries J. Implications of direct-to-consumer whole-exome sequencing in South Africa. S. Afr. Med. J. 106: 139-140 (2016).

 

19. Chaudhry M., Alessandrini M. and Pepper M.S. Pharmacogenomics for infectious diseases in sub-Saharan Africa: successes and opportunities. Appl. Translational Genomics. 9: 3-5 (2016).

 

20. Nicholson S.A and Pepper M.S. CRISPR-Cas: revolutionising genome engineering. S. Afr. Med. J. 106: 870-871 (2016).

 

21. Alessandrini M., Chaudhry M., Dodgen T.M. and Pepper M.S. Pharmacogenomics and precision medicine in the context of adverse drug reactions: top 10 opportunities and challenges for the next decade. OMICS JIB Journal. 20: 593-603 (2016).

 

22. Dessels C., Potgieter M. and Pepper M.S. Making the switch: alternatives to foetal bovine serum for adipose-derived stromal cell expansion. Frontiers Cell Dev. Biol. (section: Stem Cell Research). Vol. 4; Article 115 (2016).

 

23. Reznichenko A., Huyser C. and Pepper M.S. Mitochondrial transfer: implications for assisted reproductive technologies. Appl. Translational Genomics. 11: 40-47 (2016).

 

24. Stewart C. and Pepper M.S. Cystic fibrosis in the African diaspora. Ann. Am. Thorac. Soc. 14: 1-7 (2017).

 

25. Pepper M.S. Exporting DNA - striking a balance between preventing exploitation and promoting innovation.  S. Afr. Med. J. 107: 106-107 (2017).

 

26. Alessandrini M., Kappala S. and Pepper M.S. AMLprofiler: a diagnostic and prognostic microarray for acute myeloid leukaemia. Methods Mol. Biol. 1633: 101-123 (2017).

 

27. Arbuthnot P., Maepa M.B., Ely A. and Pepper MS. The state of gene therapy research in Africa, its significance and implications for the future. Gene Therapy 24: 581-589 (2017).

 

28. Senthebane D.A, Rowe A., Thomford N.E., Shipanga H., Munro D., Al Mazeedi M.A.M., Almazyadi H.A.M., Kallmeyer K., Dandara C., Pepper M.S., Parker M.I. and Dzobo K. The role of tumor microenvironment in chemoresistance: To survive, keep your enemies closer. Int.J.Mol. Sci. 18: E1586 (2017).

 

29. Lévigne, D., Modarressi A., Pepper, M.S. and Pittet-Cuénod, B. Reactive oxygen species and NOX enzymes are emerging as key players in cutaneous wound repair. Int. J. Mol. Sci. 18: 2149; 1-28(2017).

 

30. Helena J.M., Joubert A.M., Grobbelaar S., Nolte E.M., Nel M., Pepper M.S., Coetzee M. and Mercier A.E. Deoxyribonucleic acid damage and repair: capitalizing on our understanding of the mechanisms of maintaining genomic integrity for therapeutic purposes. Int. J. Mol. Sci. 19(4) (2018).

 

31. Dessels C., Alessandrini M., Pepper M.S. Factors influencing the umbilical cord blood stem cell industry: an evolving treatment landscape. Stem Cells Translational Med. 7: 643-650 (2018).

 

32. van Rensburg J., Alessandrini M., Stewart C. and Pepper M.S. Cystic fibrosis in South Africa: a changing diagnostic paradigm. S. Afr. Med. J. 108: 624-628 (2018).

 

33. Anderson R., Theron A.J., Nel J.G., Durandt C., Cholo M.C., Feldman C. and Tintinger G.R. Clofazimine, but Not Isoniazid or Rifampicin, Augments Platelet Activation in vitro. Front Pharmacol – Inflam Pharmacol. 9: 1335 (2018).

 

34. Pepper M.S., Alessandrini M., Pope A., van Staden W. and Green R.J. Cell and gene therapies at the forefront of innovative medical care: implications for South Africa. S. Afr. Med. J. 109: 20-22 (2019).

 

35. Pepper M.S., Pope A., Kling S., Alessandrini M., van Staden W. Green R.J. Ethical considerations in the application of cell and gene therapies in children. S. Afr. Med. J. 108: 1027-1029 (2018).

 

36. Pepper M.S., Dandara C., de Vries J., Dhai A, Labuschaigne M., Mnyongani F., Moodley K., Olckers A., Pope A., Ramesar R., Ramsay M., Soodyall H. and Towers, W. Consensus Study on the Ethical, Legal and Social Implications of Genetics and Genomics in South Africa. S. Afr. J Science In press (2018).

 

37. Wolmarans E., Nel S., Durandt C., Mellet J. and Pepper M.S. Side population: its use in the study of cellular heterogeneity and as a potential enrichment tool for rare cell populations. Stem Cells Int. Volume 108: Article ID 2472137, 7 pages (2018).

 

38. du Plessis L., Bonato M., Durandt C., Cloete S.W.P. and Soley J.T. Sperm macrocephaly syndrome in the ostrich Struthio camelus: morphological characteristics and implications for motility. Reprod Fertil Dev. (2018).

 

Book chapters:

 

1. Botes M.W., Slabbert M.N., Alessandrini M. and Pepper M.S. Stem cell therapy: accepted therapies and managing the hope of society. In Stem Cells in Clinical Applications. Series Ed.: Pham, Phuc Van. Springer. 1-35 (2016).

 

2. van Vollenstee F.A., Hoffmann D. and Pepper M.S. Harvesting and collection of adipose tissue for the isolation of adipose-derived stromal/stem cells. In Stem Cells in Clinical Applications. Series Ed.: Pham, Phuc Van. Springer. 131-161 (2016).

 

3. van Vollenstee F.A., Kallmeyer K., Dessels C., de Villiers D., Potgieter M., Durandt C. and Pepper M.S. Isolation and characterization of adipose-derived stromal cells. In Stem Cells in Clinical Applications. Series Ed.: Pham, Phuc Van. Springer. 199-220 (2016).

 

4. Steel H.C., Alessandrini M., Mellet J., Dessels C., Oloyo A. and Pepper M.S. Cord blood stem cell banking. In Stem Cells in Clinical Applications. Series Ed.: Pham, Phuc Van. Springer. 163-180 (2016).

 

5. Pepper M.S. and Saurat J.-H. Eléments d’angiogenèse cutanée. In: Dermatologie et infections sexuellement transmissibles, 6ème édition. J.-H. Saurat, et al., Eds. Elsevier Masson (Paris).  754-755 (2017).

 

6. Jackson C.S., Alessandrini M. and Pepper M.S. Clinical safety and applications of stem cell gene therapy. In Stem Cells in Clinical Applications. Series Ed.: Pham, Phuc Van. Springer. 67-89 (2017

 

7. Mabeta P. and Pepper M.S. Manipulating the tumor microenvironment: opportunities for therapeutic targeting. In: Frontiers in Anti-Cancer Drug Discovery. Atta-ur-Rahman & M. Iqbal Choudhary (Eds.) Bentham Science Publishers.  Vol. 8: 3-32 (2017). 

 

8. Alessandrini M., Kappala S. and Pepper M.S. AMLprofiler: a diagnostic and prognostic microarray for acute myeloid leukaemia. In: Acute Myeloid Leukemia, Methods and Protocols. Paolo Fortina,  MD PhD, Eric Londin, PhD, Jason Park, MD PhD, and Larry Kricka, PhD, Eds. Springer Science and Business Media, LLC, New York.  101-123 (2017).

 

9. de Villiers D., Potgieter M., Ambele M.A., Adam L., Durandt C., Pepper M.S.  The Role of Reactive Oxygen Species in Adipogenic Differentiation. In: Van Pham P. (eds) Stem Cells: Biology and Engineering. Advances in Experimental Medicine and Biology. Springer, Cham. Vol. 1083; 125-144 (2018)

 

10. Oloyo A.K., Ambele M.A., Pepper M.S. Contrasting Views on the Role of Mesenchymal Stromal/Stem Cells in Tumour Growth: A Systematic Review of Experimental Design. In: Van Pham P. (eds) Stem Cells: Biology and Engineering. Advances in Experimental Medicine and Biology. Springer, Cham. Vol. 1083; 103-124 (2018).

 

11. Wolmarans E., Boy S.C., Nel S., Mercier A.E., Pepper M.S. (2017) Cancer Stem Cells in Head and Neck Carcinomas: Identification and Possible Therapeutic Implications. In: Van Pham P. (eds) Stem Cells: Biology and Engineering. Advances in Experimental Medicine and Biology, vol 1083. Springer, Cham . Vol 1083; 89-102 (2018).

 

12. Meisner-Roloff M., Gaggia L., Vermeulen M., Haeri Mazanderani A., du Plessis N.M., Steel H. and Pepper M.S. Strategies for screening cord blood for a public cord blood bank in high HIV prevalence regions. In: Stem Cells in Clinical Applications: Stem cell banks. Series Ed.: P.V. Pham, Springer International Publishing (Switzerland). In press (2017).

 

13. Dessels C., Alessandrini M., Pepper M.S. The evolution of the use of umbilical cord blood for therapeutic purposes. In: Stem Cells in Clinical Applications: Stem cell banks. Series Ed.: P.V. Pham, Springer International Publishing (Switzerland). In press (2017).

 

14. Jackson C.S, Myburgh R., Salmon P., Krause K.H., Speck R.F. and Pepper M.S. Clinical applications of genetically modified hematopoietic stem cells. In: Stem Cells in Clinical Applications: Stem Cells for Cancer and Genetic Disease Treatment. Series Ed.: P.V. Pham, Springer International Publishing (Switzerland). In press (2017).

 

 

 

Published Abstracts of Conference proceedings:

 

 

1. Mabeta P., Davis P.F. and Pepper M.S. mTOR/PI3k/Akt signalling pathway in tumor angiogenesis and therapeutic targeting. Anticancer Res. 34: 6042, 2014. 9th International Anti Cancer Conference, Sithonia, Greece, 6-10 October 2014.

 

2. Theron A.E., Lafanechere L., Pepper M.S., Prudent R., Viallet J., Jackson C., du Rant C and Joubert A.M. Novel in silico-designed anti-cancer compounds: from in vitro exploration to potential clinical considerations. J. Cancer Sci. Ther. 6: 10, 2014. 4th World Congress on Cancer Science & Therapy, Chicago, USA, 20-22 October 2014.

 

3. Alessandrini M. and Pepper M.S. Priority pharmacogenetics for Africa: establishment of a pan-African initiative. Basic Clin. Pharmacol. Toxicol. 115 (Suppl 1), 169, 2014. 17th World Congress of Basic and Clinical Pharmacology, Cape Town, SA, 13-18 July 2014.

 

4. Myburgh R., Ivic S., Pepper M.S., Gers-Huber G., Li D., Audige A., Rochat M.A., Jaquet V., Regenass S., Salmon P., Krause K.H. and Speck R.F. Lentivector knock-down of CCR5 in hematopoietic stem cells confers functional and persistent HIV-1 resistance in humanized mice. Mol. Ther. 23 (Suppl. 1), S178, 2015. American Society of Gene & Cell Therapy 18th Annual Meeting, New Orleans, LA. 13-16 May 2015.

 

5. Kallmeyer K., Pepper M.S., Pittet-Cuenod B. and Modarressi A. In vitro tracking of adipose-derived mesenchymal stromal cells during physiological wound repair. Plast. Reconstr. Surg. S. 8th European Plastic Surgery Research Council (EPSRC) Meeting. Brussels, Belgium. 25-26 May 2016.

 

6. Naidoo, V. Ramsuran, M. Chirehwa, P. Denti, H. McIlleron, K. Naidoo, N. Yende-Zuma, R. Singh, S. Ngapu, M. Pepper, M. Chaudhry, and N. Padayatchi. The Effect of Genetic Variation in UGT1A and ABCB1 on Moxifloxacin Pharmacokinetics in South African Patients with Tuberculosis. Clinical Therapeutics, Volume 39, Issue 8, Supplement, Pages e44–e45. The Proceedings of the 13th Congress of the European Association for Clinical Pharmacology and Therapeutics. Prague, Czech Republic, 23-27 June 2017.

 

7. Oloyo A.K., Ambele M and Pepper M.S. Contrasting views on the role of mesenchymal stem cells in tumour progression: a systematic review. Cancer Res. 77 (Suppl. 22). Abstract B36. Proceedings of the AACR International Conference; New Frontiers in Cancer Research, Cape Town, South Africa, 18-22 January 2017.

 

Policy document

Pepper M.S., Dandara C., de Vries J., Dhai A, Labuschaigne M., Mnyongani F., Moodley K., Olckers A., Pope A., Ramesar R., Ramsay M., Soodyall H. and Towers, W. Human Genetics and Genomics in South Africa: Ethical, Legal and Social Implications. Consensus Study conducted on behalf of the Academy of Science of South Africa. December 2018. (117 pages)

 

update 22/05/2019