Biocatalysis and integration of metabolism 357

Modulekode BCM 357
Kwalifikasie Undergraduate
Fakulteit Faculty of Natural and Agricultural Sciences

Regulation of metabolic pathways. Analysis of metabolic control. Elucidation of metabolic pathways with isotopes. Metabolomics. Coordinated regulation of glycolysis/gluconeogenesis and glycogen breakdown/synthesis. Overview of homone action. Metabolism of xenobiotics. Hormonal regulation of feul metabolism. Metabolic adaptions during diabetes. Obesity and the regulation of body mass. Obesity, metabolic syndrome and Type 2 diabetes (T2D). Management of T2D with diet, exercise and medication. Practical sessions cover tutorials on case studies and biochemical calculations, and hands-on isolation of an enzyme, determination of pH and temperature optima, determination of Km and Vmax, enzyme activation and enzyme inhibition. 

Modulekrediete 18.00
NQF Level 07
Prerequisites BCM 251 GS and BCM 257 GS and BCM 261 GS and BCM 252 GS.
Contact time 1 practical/tutorial per week, 2 lectures per week
Language of tuition Module is presented in English
Department Biochemistry, Genetics and Microbiology
Period of presentation Semester 1

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